A facile and convenient strategy for the assembly of N-arylated heterocycles has been demonstrated using a MnCl2.4H2O/trans-1,2-diaminocyclohexane catalyst and K3PO4 as the base in water.
An efficient and mild method using a bimetallic MnF2/CuI catalyst at 60 °C in water was developed for the N‐arylation of amides and sulfonamides with aryl halides. A variety of functionalized amides and sulfonamides were coupled with different substituted aryl halides to afford the corresponding N‐arylated products in good to excellent yields (up to 97 %).
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