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This study was designed to explore the effect of active immunization against maltose binding protein-gonadotropin releasing hormone I hexamer (MBP-GnRH-I6) on the reproductive function in cats. Each immunized cat was administered twice intramuscularly in the neck at 16 and 20 weeks old. The concentrations of the testosterone and estradiol and the level of anti-GnRH-I antibody in the serum were measured by radioimmunoassay and ELISA, respectively. The results showed that the weight and size of testicles and ovaries, and the concentrations of serum testosterone and estradiol in the immunized animals were lower than those of the control cats (P < 0.05), but that the levels of anti-GnRH-I antibody were significant higher compared to control animals (P < 0.05). Testicular tissues from the immunized male cats showed that seminiferous tubules were depauperate with the lumen relatively empty and that the differentiation of spermatogonia was not obvious. Tissues from the immunized female cats showed that the ovaries had many primordial follicles and primary follicles, but no secondary follicle was observed. These results showed active immunization against MBP-GnRH-I6 could make the gonads atrophy and reduce the concentrations of gonadal hormones, which suggested that MBP-GnRH-I6 was a very effective immunogen in the cat.

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Integrally geared multistage centrifugal compressors have been widely used in many industries. The design of the new compressor is very complicated and needs a reliable design process. This paper discussed the development of a high efficiency integrally geared driven centrifugal compressor for industrial applications. An inhouse program was used to design the centrifugal compressor through aerodynamic and structural optimization. CFD (Computational Fluid Dynamics) is a very important tool for centrifugal compressor design. CFD can help compressor design and perform three-dimensional optimization to further optimize the compressor. The compressor stage matching is also impact the overall compressor performance. The good stage match is very important to make the design success. The Finite Element Analysis (FEA) was used to verify the structure integrity. The CFD and FEA (Finite Element Analysis) analysis are performed to obtain a final compressor performance and to make sure to have a robust operation. The centrifugal compressor has the characteristics of high efficiency, no resonance, and low noise. The designed compressor prototype was built and performance tests were conducted. The performance test results demonstrated that the analytical are fairly agreed with experimental results. The development process and tools are successfully used in the compressor design. The design process can be used for future compressor development.

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This study assessed the discrepancies between reports from parents and children concerning children's exposure to violence/pornography on mobile devices and the impact on the psychosocial adjustment of children. Data were obtained from a sample of 2,230 parent-child dyads recruited from 16 elementary schools (1,140 dyads) in Taiwan and 9 schools (1,090 dyads) in China. A self-administered questionnaire was used. The results showed that about 30 percent of children reported being exposed to violence on mobile devices. Approximately 70 percent of their parents were unaware of their child's exposure to violence on mobile devices. About 16 percent of children reported exposure to pornography on mobile devices, and 80 percent of their parents were unaware of this exposure. Multinomial logistic regression results showed that after controlling for parent and child sociodemographic variables, factors related to parental unawareness of child exposure to violence on mobile devices included a child's ownership of mobile devices, smartphone/tablet use time, a lower level of parental understanding, and a residence in China or in a rural area, whereas the parent-child relationship and a child's smartphone/tablet use time were associated with parents who were unaware of their child's exposure to pornography. Multiple regression results showed that children who were living with household poverty, had a poor parent-child relationship, spent much time using a smartphone/tablet, and with parents who were unaware of their exposure to violence/pornography on mobile devices were more likely to have emotional and behavioral problems.

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