Glucose-6-phosphate dehydrogenase (G6PD) protects erythrocytes from oxidative stress and hemolysis; G6PD deficiency is the most prevalent enzymopathy. The United States military routinely performs tests to prevent exposing G6PD-deficient personnel to antimalarial drugs that might cause life-threatening hemolytic reactions. In addition, G6PD is a key determinant of vascular function, and its deficiency can lead to impaired nitric oxide production and greater vascular oxidant stress-precursors to atherosclerosis and cardiovascular disease. Using military medical records, we performed a retrospective, cross-sectional study to investigate whether deficient G6PD levels are associated with a higher prevalence of cardiovascular disease than are normal levels, and, if so, whether the relationship is independent of accepted cardiovascular risk factors. We analyzed the medical records of 737 individuals who had deficient G6PD levels and 16,601 who had normal levels. Everyone had been screened at U.S. military medical centers from August 2004 through December 2007. We evaluated our dependent variable (composite cardiovascular disease) at the individual level, and performed binary logistic regression of our independent variable (G6PD status) and control variables (modifiable cardiovascular risk factors). The adjusted odds ratio of 1.396 (95% CI, 1.044-1.867; <0.05) indicated that G6PD-deficient individuals have 39.6% greater odds of developing cardiovascular disease than do those with normal levels. Early intervention may reduce the incidence of cardiovascular disease in military personnel and civilians who have deficient G6DP levels.

Diffusion of Innovations and the Theory of Planned Behavior provide the foundation on which a preponderance of information systems (IS) theory and research is built. IS scholars often assume that the basic factors proffered by these theories are significant determinants of innovation adoption. However, there has yet to be a meta-analytic examination of research in the IS field to validate this assumption. Herein, we use Tornatzky and Klein's seminal 1982 meta-analysis of innovation characteristics as the starting point for our meta-analytic examination of Diffusion of Innovations and Theory of Planned Behavior models in IS research. In order to focus our investigation on a common criterion variable, adoption propensity, we use antecedents from both models to develop a model of innovation adoption-behavior (IAB). After describing the relationships encompassed by the IAB model, we step through a bare-bones meta-analysis. Considering the data reported in fifty-eight empirical articles, we calculate the estimated true correlations with the criterion variable to be .53 for attitude toward behavior, .33 for subjective norm, .41 for perceived behavioral control, .42 for relative advantage, .43 for compatibility,-.28 for complexity, .32 for trialability, and .38 for observability. With the exception of complexity, all correlations generalize across studies.

If you would like to write for this, or any other Emerald publication, then please use our Emerald for Authors service information about how to choose which publication to write for and submission guidelines are available for all. Please visit www.emeraldinsight.com/authors for more information. About Emerald www.emeraldinsight.comEmerald is a global publisher linking research and practice to the benefit of society. The company manages a portfolio of more than 290 journals and over 2,350 books and book series volumes, as well as providing an extensive range of online products and additional customer resources and services.Emerald is both COUNTER 4 and TRANSFER compliant. The organization is a partner of the Committee on Publication Ethics (COPE) and also works with Portico and the LOCKSS initiative for digital archive preservation. AbstractPurpose -Information systems (IS) play a substantial role in managing reverse logistics (RL) processes. However, the RL literature rarely takes a holistic approach to examining the "success" of IS employment. Drawing on the rich literature base from the IS field, the authors explore IS Success theory in the context of RL. Considering Diffusion of Innovation theory, the authors also examine the effect of motivation on IS utilization. In doing so, the authors provide scholars and practitioners with insight into the factors affecting the success of a RL IS. The paper aims to discuss these issues. Design/methodology/approach -Based upon DeLone and McLean's IS Success theory, the authors develop the model to consider information quality, IS utilization, and RL cost effectiveness (as a proxy for net benefits). The authors disaggregate RL into two processes and thus consider the model from two perspectives: the process of receiving returns from customers (inbound) and the process of returning products to suppliers (outbound). The authors survey 136 RL professionals and employ partial least squares modeling for data analysis. Findings -For both inbound and outbound path models, information quality is significantly and positively related to IS utilization; in turn, IS utilization is a significant predictor of net benefits. For inbound, RL goals provide significant motivation to drive IS utilization. For outbound, RL challenges provide significant motivation for IS utilization. Originality/value -The authors bring IS Success theory into the context of RL. Additionally, by investigating the topic from both inbound and outbound perspectives, the findings suggest differences between inbound and outbound RL processes.

Background: The relationship between open access and patient satisfaction is mixed. Our study is the first to assess the relationship between open access appointment scheduling and patient satisfaction in the Military Health System (MHS). It is also unique in that we examine both same-day and 24-hour access through a relationship with satisfaction. Methods: We conducted a panel time-series analysis with general estimating equations on the Army population of outpatient facilities (N = 32), with 32 364 957 total observations. Our primary independent variables were the proportion of a facility's appointments within 24 hours and same day from July 2013 to May 2015. Results: We identified that a higher proportion of same-day appointments is associated with increased patient satisfaction with the ability to see their provider when needed. We did not find the same result when examining access within 24 hours. Conclusions: Open access appointment scheduling appears to have a greater impact on patient satisfaction with timeliness of care if that appointment is made the same day the patient presents to the facility. Facilities should consider opening more of their schedule to accommodate same-day appointments. This can result in less costly primary care instead of emergency department usage.