This study reports, for the first time, the association between GDF5 polymorphisms and CDH in Caucasians, and points out another polymorphism of interest that requires further investigation. Reduction in GDF5 expression might lead to developmental deficiency of ligaments and capsule in hip joint, and therefore contribute to CDH pathogenesis.
A cemented dual mobility cup was able to restore hip stability in 94% of patients presenting with recurrent dislocating hips up to 13-year follow-up with none of the complications associated with constrained devices, as mechanical failure occurred in only 3.9% of the patients of this series. The overall reduced survival using revision for any reason as the end-point at ten years was related to this specific patients population that had various co-morbidities.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.