The presence of rhabdomyolysis secondary to multiple infections has been reported, predominantly viral, but also bacterial and fungal. It is well known that COVID-19 can present a wide variety of complications during the course of infection; however, the presence of rhabdomyolysis as an initial condition has not been reported so far. We report a case of rhabdomyolysis as an initial presentation in a patient diagnosed with SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2) infection.
BackgroundChagas disease (CD) is caused by the protozoan parasite Trypanosoma cruzi and is transmitted by triatomine insects. Clinical manifestations vary according to the phase of the disease. Cutaneous manifestations are usually observed in the acute phase (chagoma and Romaña’s sign) or after reactivation of the chronic phase by immunosuppression; however, a disseminated infection in the acute phase without immunosuppression has not been reported for CD. Here, we report an unusual case of disseminated cutaneous infection during the acute phase of CD in a Mexican woman.MethodsEvaluation of the patient included a complete clinical history, a physical exam, and an exhaustive evaluation by laboratory tests, including ELISA, Western blot and PCR.ResultsSkin biopsies of a 50-year-old female revealed intracellular parasites affecting the lower extremities with lymphangitic spread in both legs. The PCR tests evaluated biopsy samples obtained from the lesions and blood samples, which showed a positive diagnosis for T. cruzi. Partial sequencing of the small subunit ribosomal DNA correlated with the genetic variant DTU II; however, serological tests were negative.ConclusionsWe present a case of CD with disseminated skin lesions that was detected by PCR and showed negative serological results. In Mexico, an endemic CD area, there are no records of this type of manifestation, which demonstrates the ability of the parasite to initiate and maintain infections in atypical tissues.
Key Clinical MessageInvolvement of the central nervous system in sarcoidosis is rare; neurosarcoidosis, although unusual, can present as leptomeningitis. The diagnosis is usually difficult because of the vague and broad symptomatology; therefore, a prompt diagnosis should be made, and adequate treatment should be administered to reduce morbidity and mortality.
La restauración de tierras forestales requiere datos relacionados con el número de plántulas producidas y el nivel de degradación del suelo. Los tomadores de decisiones necesitan saber cuáles son los esfuerzos del programa nacional de reforestación como impulsor de la restauración de ecosistemas en México. Para evaluar el potencial de restauración de los bosques de coníferas y reducir la degradación de tierra en Zonas de Movimiento de Germoplasma (ZMG), se compararon zonas prioritarias para la restauración con los esfuerzos de reforestación más efectivos: porcentaje de sobrevivencia de plántulas plantadas, número de viveros (N), unidades de producción de germoplasma (UPG) y bancos de germoplasma (BG); para ello, se usó la base de datos de la Conafor correspondiente al periodo de 2016 a 2018. Se determinó que 27 ZMG tenían tierras forestales como áreas prioritarias: 7 418 975.30 ha de baja producción y 9 389 577.70 ha de degradación media y baja. De acuerdo con las variables utilizadas en el análisis comparativo, se identificaron ocho ZMG (XII.4, XII.5, X.3, X.2, XII.1, V.3, XII.2 y XV.1) como zonas de mayor potencial para la restauración, debido a que sus áreas prioritarias podrían ser reforestadas totalmente con especies de Pinus y Abies.
Landscape modification and habitat fragmentation are key drivers of global species and biodiversity loss, as well as a major threat to the conservation of forest ecosystems. Mexico is one of the five biologically richest countries in the world. This study first generated a national level assessment Transitions between forest fragmentation classes were relatively small compared to transitions to no-forest land covers, and transitions to higher fragmentation classes were slightly larger in tropical than in temperate forests.
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