ResumenEl artículo pretende analizar la voluntad democrática de la sociedad y los actores políticos para mirar con certidumbre el porvenir democrático de México; aborda el proceso institucional en que está inmerso y observa que en esta conducción se tiene al Parlamento como baluarte. A partir de una revisión documental, se afirma que el fortalecimiento de los procedimientos de control parlamentario en México permitirá enjuiciar públicamente la actuación del poder ejecutivo, al brindar a la opinión pública la ocasión de conocer, a través de las críticas y censuras de la oposición, los errores y omisiones del Gobierno, siendo este mecanismo una vía para que el Gobierno se sienta vigilado, que evite hacer algo que pueda parecer incorrecto, convirtiéndose en un papel preventivo frente a posibles abusos. Esta investigación propone comprender que en la democracia se requiere de responsabilidad compartida al momento de ser ejercida por los poderes públicos y la sociedad en los temas de interés general.

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The influence of diabetes on endothelial mechanisms implicated in the response of isolated rabbit carotid arteries to 5-hydroxytryp-Ž . tamine 5-HT was studied. 5-HT induced a concentration-dependent contraction that was potentiated in arteries from diabetic rabbits with respect to that in arteries from control rabbits. Endothelium removal potentiated 5-HT contractions in arteries from both control and diabetic rabbits but increased the maximum effect only in arteries from diabetic rabbits. Incubation of arterial segments with G Ž . N -nitro-L-arginine L-NA enhanced the contractile response to 5-HT. This L-NA enhancement was greater in arteries from diabetic rabbits than in arteries from control rabbits. Aminoguanidine did not modify the 5-HT contraction in arteries from control and diabetic rabbits. Indomethacin inhibited the 5-HT-induced response, and this inhibition was higher in arteries from control rabbits than in arteries from diabetic rabbits. In summary, diabetes enhances the sensitivity of the rabbit carotid artery to 5-HT. In control animals, the Ž . endothelium modulated the arterial response to 5-HT by the release of both nitric oxide NO and a vasoconstrictor prostanoid. Diabetes enhances endothelial constitutive NO activity and impairs the production of the endothelial vasoconstrictor. q

The influence of diabetes on the response of isolated rabbit renal arteries to 5-hydroxytryptamine (5-HT) was examined. 5-HT induced a concentration-related contraction that was higher in arteries from diabetic rabbits than in arteries from control rabbits. Endothelium removal did not significantly modify 5-HT contractions in arteries from control rabbits but enhanced the response to 5-HT in arteries from diabetic rabbits. Incubation with N G -nitro-L-arginine (L-NA) enhanced contractions to 5-HT in arteries from control and diabetic rabbits. In arteries with endothelium, this L-NA enhancement was lower in diabetic rabbits than in control rabbits. In arteries without endothelium, incubation with L-NA enhanced the maximal contractions to 5-HT in control rabbits but did not in diabetic rabbits. Indomethacin inhibited 5-HT-induced contraction of arteries from control rabbits and enhanced the maximal contraction to 5-HT of arteries from diabetic rabbits. In summary, diabetes enhances contractile response of rabbit renal artery to 5-HT. In control animals, this response is regulated by both endothelial and non-endothelial (neuronal) nitric oxide (NO) and by a vasoconstrictor prostanoid. Diabetes impairs the release of non-endothelial NO and the vasoconstrictor prostanoid. D