P ercutaneous coronary intervention with stent implantation is the standard of care in patients with ST-segmentelevation myocardial infarction (STEMI). 1 Patients treated with first-generation drug-eluting stents (DES) had lower rate of target lesion revascularization than patients treated with bare-metal stents (BMS) at 5 years.2 However, this reduction was only observed during the first year after stent implantation. The analysis of the subsequent years (from 1-5 years) showed higher rate of target lesion revascularization in the group treated with first-generation DES than in the group treated with BMS. This was caused by a higher incidence of very-late stent thrombosis (ST) in the group treated with firstgeneration DES.2 Moreover, it is also remarkable that the incidence of late ST has no attenuation neither with DES nor with BMS at very long-term follow-up (>5 years).
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