El Gran Catharro (1580) es considerado como la primera epidemia de gripe. El análisis conjunto de los datos contenidos en diferentes testimonios, suscita dudas respecto a que se tratara de una epidemia de gripe y apoyan la posibilidad de que se tratara de una de tos ferina.
The surgeon Federico Rubio-Gali is mentioned in connexion with Florence Nightingale. In different publications giving him a prominence in the development of the modern Spanish nursing profession. With this work we propose to analyze the influence that Nightingale could have had over Rubio-Gali. We want to analyse the life and works of the founder of the School of Nurses of Santa Isabel de Hungría establishing the intellectual temporary and spatial coincidences with the Lady of the Lamp. Our objective is to establish the parallelisms between both lives and examine the possible impact of Nightingale in the beginnings of the modern Spanish nursing. The analysis of primary and secondary documental sources was the technique chosen to compare the biography and works of Nightingale and RubioGali. Some of the similarities founded, e.g. in the syllabuses of their respective schools and different health measures would confirm the influence of Nightingale in Rubio-Gali, nevertheless, only in Hernández (1996), Nightingale is recognised as a key point in the contributions of Rubio-Gali.
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