Granular cell tumor most commonly appears in the tongue and skin, but has been found in varied locations (10). There are now 14 reported cases of the lesion occurring in the common bile duct. In most of these 14 cases, it has affected black females in their thirties. The lesion is most often benign. It should be considered in the differential diagnosis of obstructive jaundice secondary to bile duct tumors, especially if other granular cell tumors are present. This is the first reported case of pancreaticoduodenectomy for granular cell tumor of the common bile duct.
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