Fig 2.-A neurofibroma with fusiform cells in a fine fibrillar stroma is seen in the upper two thirds of the reticular dermis (hematoxylin-eosin, X25). ous observations of others56 suggest that PUVA treatment acts as a stabilizer for mast cells, both in animal and in hu¬ man skin. At present, we consider that the atypical cutane¬ ous neurofibromas occur independently from psoriasis or PUVA treatment; however, we can not exclude an unrecog¬ nized role of PUVA treatment for the development of neurofibroma.

No abstract