No consensus yet exists on how to handle incidental fnd‐ings (IFs) in human subjects research. Yet empirical studies document IFs in a wide range of research studies, where IFs are fndings beyond the aims of the study that are of potential health or reproductive importance to the individual research participant. This paper reports recommendations of a two‐year project group funded by NIH to study how to manage IFs in genetic and genomic research, as well as imaging research. We conclude that researchers have an obligation to address the possibility of discovering IFs in their protocol and communications with the IRB, and in their consent forms and communications with research participants. Researchers should establish a pathway for handling IFs and communicate that to the IRB and research participants. We recommend a pathway and categorize IFs into those that must be disclosed to research participants, those that may be disclosed, and those that should not be disclosed.

Biobanks and archived datasets collecting samples and data have become crucial engines of genetic and genomic research. Unresolved, however, is what responsibilities biobanks should shoulder to manage incidental findings (IFs) and individual research results (IRRs) of potential health, reproductive, or personal importance to individual contributors (using “biobank” here to refer to both collections of samples and collections of data). This paper reports recommendations from a 2-year, NIH-funded project. The authors analyze responsibilities to manage return of IFs and IRRs in a biobank research system (primary research or collection sites, the biobank itself, and secondary research sites). They suggest that biobanks shoulder significant responsibility for seeing that the biobank research system addresses the return question explicitly. When re-identification of individual contributors is possible, the biobank should work to enable the biobank research system to discharge four core responsibilities: to (1) clarify the criteria for evaluating findings and roster of returnable findings, (2) analyze a particular finding in relation to this, (3) re-identify the individual contributor, and (4) recontact the contributor to offer the finding. The authors suggest that findings that are analytically valid, reveal an established and substantial risk of a serious health condition, and that are clinically actionable should generally be offered to consenting contributors. The paper specifies 10 concrete recommendations, addressing new biobanks and biobanks already in existence.

To reveal students' conceptual understanding of gas laws, this study focused on the understanding and application of scientific concepts in practical situations instead of the use of mathematical calculations in theoretical situations. One hundred and nineteen 11th grade students and 36 high school chemistry teachers participated in this study. We found that even very capable students possess alternative conceptions that are resistant to change. Moreover, analysis of the teachers' problem responses revealed that teachers and students held similar alternative conceptions of gases. These results indicated that not only chemistry teachers but also science educators should be encouraged to pay more attention to concept-based pedagogy.

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This paper reviews empirical research on the use of evaluation from 1986 to 2005 using Cousins and Leithwood’s 1986 framework for categorizing empirical studies of evaluation use conducted since that time. The literature review located 41 empirical studies of evaluation use conducted between 1986 and 2005 that met minimum quality standards. The Cousins and Leithwood framework allowed a comparison over time. After initially grouping these studies according to Cousins and Leithwood’s two categories and twelve characteristics, one additional category and one new characteristic were added to their framework. The new category is stakeholder involvement, and the new characteristic is evaluator competence (under the category of evaluation implementation). Findings point to the importance of stakeholder involvement in facilitating evaluation use and suggest that engagement, interaction, and communication between evaluation clients and evaluators is critical to the meaningful use of evaluations.

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This study investigated how affective factors impact participation in science learning using structural equation modeling. Using a dataset from Taiwan, a model was obtained that showed the relationships among science-related interest, enjoyment, self-efficacy, self-concept, competency, leisure time engagement, and future interest in science. The paths relating to engagement and future interest were much stronger for interest and enjoyment than for self-efficacy and self-concept. There was no significant path between science competency and future science interest or engagement. The results suggest that the affective and cognitive pathways to scientific competency are divergent and that they might be differentially activated by different contexts and activities. This indicates that school science educators might wish to reconsider the merit of overemphasizing achievement in comparison to interest. Finally, the results suggest that the development of science competency per se may not be the best way to ensure public engagement and understanding of science.

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