Dietary folate and cobalamin estimates from FFQ were significantly correlated with their fasting plasma concentrations. Our data supported the validity of new FFQ to rank individuals by dietary intake status of folate and cobalamin.
Objective: We designed this study to investigate the effects of oral L-carnitine administration on fasting plasma glucose (FPG), glycosylated hemoglobin (HbA1c) and lipid parameters in patients with diabetes mellitus type II. Patients and methods: The effect of L-carnitine on FPG and lipid parameters was investigated in 22 male and 13 female type II diabetic patients; the mean age7s.d. was 51.373.7 y. The patients were randomly allocated to two groups (L-carnitine and placebo group) and 1 g of L-carnitine or of placebo was given orally three times a day for a period of 12 weeks. Results: FPG in the L-carnitine group decreased significantly from 143735 to 130733 mg/dl (P ¼ 0.03), and we observed a significant increase of triglycerides (TG) from 196761 to 233712 mg/dl (P ¼ 0.05), of Apo A1 from 94720 to 103723 mg/dl (P ¼ 0.02), and of Apo B100 from 98718 to 108722 mg/dl (P ¼ 0.02) after 12 weeks of treatment. There was no significant change in LDL-C, HDL-C, HbA1C, LP(a) or total cholesterol. Conclusion: L-Carnitine significantly lowers FPG but increases fasting triglyceride in type II diabetic patients.
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