Background: Laryngeal amyloidosis is a rare pathology of the airway in which the diagnosis can only be made via tissue biopsy. We reported a case of laryngeal amyloidosis presenting with symptoms of hoarseness and voice fatigue.Case report: This is a case report of laryngeal amyloidosis in a middle-aged female patient who presented with hoarseness of voice. Upon obtaining a further history and performing a clinical examination, it was noted that the patient had a laryngeal mass. She underwent surgery, and the mass was histopathologically confirmed as laryngeal amyloidosis. She was successfully treated with a combination of surgical and medical treatment. This case presentation describes these rare pathological findings, their clinical manifestations, the histopathological and surgical diagnostic problems, treatment and patient’s progress that we followed up till presence.Conclusion: Isolated laryngeal amyloidosis is a rare benign laryngeal tumor that is often presented with various symptoms depending on the tumor location and can even cause upper airway obstruction. It is a histological diagnosis confirmed by histopathological specimens that are stained with Congo red. Treatment of laryngeal amyloidosis includes symptomatic relief, surgical or even conservative treatment.Â
Langerhans' cell histiocytosis (LCH) is a rare group of diseases characterized by abnormal clonal proliferation of Langerhans cells in one or more systems. LCH can occur in any system. We report a case of bilateral otologic LCH that presented as a case of mastoiditis. Despite multiple courses of antibiotics, there was no improvement. Subsequent excision biopsy of a postauricular mass confirmed the diagnosis of LCH. The patient responded well to chemotherapy.
<p class="abstract">Mucoepidermoid carcinoma (MEC) is a malignant epithelial salivary gland neoplasm which consists of a mixture of mucin-producing columnar cells, epidermoid (squamous) cells and polygonal intermediate cells. Salivary gland-type carcinomas are extremely rare to be found in the nasopharynx. A 46-year-old lady presented with bilateral progressive nasal blockage and occasional epistaxis for 3 years. However, there was no neck swelling. Nasoendoscopy revealed a huge nasopharyngeal mass. Tissue biopsy in clinic setting reported of inverted papilloma. Computed tomography shows large irregular heterogenously enhancing mass in nasopharynx. Posterior septectomy was done for the access and endoscopic excision of nasopharyngeal tumor was performed. Histopathological examination confirmed the tumor is mucoepidermoid carcinoma. Postoperative adjuvant concurrent chemoradiotherapy with total of 66 Gy was commenced in view of concern of possible residual microscopic disease. Nasopharynx is an uncommon site for MEC. MEC patients seldom has enlarged neck node at presentation.Nasopharyngeal salivary gland-type carcinomas does not commonly cause cranial nerve palsy compared to nasopharyngeal carcinoma (NPC). In cases with huge nasopharyngeal mass without neck nodes and cranial nerves involvement, MEC can be a differential diagnosis. Surgical removal of gross disease and concurrent chemoradiotherapy as an adjuvant treatment for likely residual microscopic disease is the standard treatment for nasopharyngeal mucoepidermoid carcinoma.</p>
Fishbone ingestion is a common occurrence and patients present with various symptoms, posing challenges to the attending physicians. Here, we present two unique cases of patients with an unexpected rapidly migrating fishbone in the tongue. The first patient was operated transorally because of a foreign body embedded in the genioglossus muscle. In the second patient, CT scan located a fishbone embedded in the left hyoglossus muscle; however, the fishbone had to be relocated intraoperatively using bedside ultrasound guidance and was eventually found embedded within the mylohyoid muscle. The fishbone was successfully removed via transcervical approach following a failed transoral approach.
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