The book deals mainly with the mouse, rat, guinea-pig, rabbit, hamster, and monkey, and some chapters are concerned with only one or two species. Thus, there are papers on spontaneous lesions of mice with special reference to sexual dimorphism, endocrine peculiarities, alterations accompanying the growth of certain tumours and lesions related to strain and age, by Dunn; on lesions, chieflyneoplastic, of rats (Snell); on the hamster (Handler); on the rabbit, particularly diseases with a genetic background (Greene); and monkey (Weston). Musculoskeletal lesions in a variety of animals are discussed by Sokoloff, and neoplastic and non-neoplastic lesions of the reticulo-endothelial system of mice by Cosgrove and Upton. Innes lists and illustrates lesions of the respiratory tract of various species, Fleischman discusses diseases of the endocrine system of primates, dogs, rats, and mice; Bloom, spontaneous renal lesions of dogs and cats; Lehr, inflammatory and degenerative lesions of the cardiovascular system; Ruebner, Lindsey, and Melby, spontaneous liver diseases; and Blumenthal and Rogers, spontaneous and induced neoplasms of the guinea-pig. In two final chapters, Paget and Lemon compare 'conventional and S.P.F. rats' and Nelson deals with the recording and reporting of laboratory data. Useful bibliographies and a record of the related discussion appear at the end of each chapter.The book is not meant to be an encyclopaedic account of the pathology of every spontaneous disease of all laboratory animals, but it does contain a good deal of important, useful and sometimes hitherto unreported information. It is welcome in that it records, sometimes for the first time, some of the wealth of information that has been accumulated by workers greatly experienced in the field of laboratory animal pathology and makes it available to others who may be in difficulties in interpreting pathological findings in the tissues of the animals with which they are dealing.
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