The modeling and simulation of CH4-O2 combustion at high pressure requires a dedicated kinetic mechanism, such as RAMEC, to obtain a precise description of the fuel decomposition. Nevertheless, to reduce its CPU cost, the optimized and reduced chemistry method ORCh is applied and validated for a set of canonical test-cases. A very good agreement is obtained by comparison with the original RAMEC detailed mechanism. To further evaluate the efficiency of the reduced mechanism, a premixed flame expanding in a homogeneous isotropic turbulence (HIT) at high pressure along with the combustion of pocket of methane in an environment of pure oxygen, with or without HIT, are presented. The new reduced chemical mechanism performs well with a relative error of 4% for the maximum of temperature in the premixed case and 6% for the non-premixed one.
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