This study suggests that a treatment of neonatal abstinence syndrome with clonidine in omission of opiates is possible without causing short-term adverse cardiovascular effects. Considering the retrospective design of the study, controlled and prospective trials are needed.
We report on a 10-year-old girl with severe aplastic anaemia who developed rhinocerebral infection caused by Absidia corymbifera and a possible co-infection caused by Alternaria alternata. Despite prolonged neutropenia, therapy with liposomal amphotericin B and posaconazole improved the clinical condition. Subsequently, the girl underwent allogeneic haematopoietic stem cell transplantation (HSCT) for the underlying disease, but the fungal infection remained under control with the antifungal treatment. No severe side effect of the antifungal drugs was noted. Unfortunately, the girl died 5 months after HSCT due to disseminated adenovirus infection.
We present the case of a 40 day old term female infant with rapidly increasing swelling of the face and neck due to undiagnosed Superior Vena Cava (SVC) syndrome. We successfully intubated the trachea using a videolaryngoscope after a failed fibreoptic intubation attempt. The possibility of thrombus and inflammation resulting in SVC obstruction should be considered following previous Internal Jugular Vein (IJV) cannulation. Videolaryngoscopes, such as the paediatric C-MAC® D-Blade, can be a valuable adjunct for a difficult airway algorithm in infants.
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