Objetivo: mensurar o conhecimento e preparo de graduandos do 3° e 4° anos de enfermagem e do 5° e 6° anos de medicina da FAMERP, em relação a conduta inicial ao paciente vítima de acidente com queimaduras, para saber o que os graduandos da área da saúde conhecem sobre o atendimento inicial ao paciente queimado. Metodologia: Estudo transversal com delineamento descritivo, abordagem quantitativa do tipo analítica com correlação entre variáveis. Foram coletadas informações existentes em 71 registros, realizado com aplicação de três questionários: (questionário 1. Atendimento inicial ao queimado - interesse pessoal e contato prévio; questionário 2a) Questões sobre atendimento inicial ao queimado- enfermagem; questionário 2b) Questões sobre atendimento inicial ao queimado- medicina) todos com perguntas fechadas, destinadas à área de conhecimento de cada curso sobre o tema tratado, aplicados a 53 alunos dos terceiro e quarto anos de enfermagem e 18 alunos do internato da medicina, em modelo formulário da plataforma google forms, enviado online. Posteriormente, os dados foram tabulados e analisados. Resultados: Os alunos de enfermagem demonstraram conhecimento considerado mediano em relação ao atendimento inicial ao paciente queimado, enquanto os alunos de medicina demonstraram conhecimento baixo. Conclusão: Os acadêmicos não possuem conhecimento suficiente para o atendimento inicial ao paciente queimado, havendo grandes dificuldades e incertezas na abordagem do tema.
Genetic changes in platelet serotonin receptors (5-HTR2A) impair the initial process of tissue repair, regardless of the triggering factor of the skin wound. Objective was to determine the prevalence of the 102T-C polymorphism in the 5-HTR2A gene in Brazilian patients with and without skin wounds. Crosssectional case-control study, in which 100 patients were evaluated as Cases Group (subdivided into I-with Chronic Wound and II-with Acute Wound) and 100 individuals as Controls, of both genders. DNA was extracted from leukocytes of peripheral blood and the region that covers the polymorphism was amplified by the molecular techniques Polymerase Chain Reaction/Restriction Fragment Length Polymorphism. The TT genotype was significantly associated with the protective factor against alterations in the healing process of skin wounds (OR: 0.4833; 95%CI: 0.2704-0.8638; p<0.05) in the Control Group. The genotypic analysis between Cases Group (I-Chronic Wound and II-Acute Wound) determined that the TT genotype was significantly associated with the protection factor in Case II (OR: 0.3333; 95%CI: 0.1359-0.8177; p<.005) and the CC genotype was significantly associated with the chance to develop chronic ulcers in the Case I (OR: 6.667; 95%CI: 1.801-24.683; p<0.05). Patients with chronic skin wounds have a higher prevalence of the 102T-C polymorphism in the 5-HTR2A gene, which is associated to alterations in the healing process in this population. There are differences, at the molecular level, in patients, with and without these lesions, and the probable role of the serotonergic system in wound healing.
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