This paper describes the rationale for a randomized controlled trial, comparing cognitive behavior therapy in addition to treatment as usual with treatment as usual alone, for borderline personality disorder. Previous pioneering randomized controlled trials of psychotherapies have suffered from methodological weaknesses and have not always been reported clearly to allow adequate evaluation of either the individual study or comparisons across studies to be undertaken. We report on the recruitment and randomization, design, and conduct of an ongoing randomized controlled trial of one hundred and six patients with borderline personality disorder. Primary and secondary hypotheses and their planned analyses are stated. The baseline characteristics of 106 patients meeting diagnostic criteria for borderline personality disorder are described.
This article analyses the specific ways in which Latin American countries have judicialised domestic violence over the last decade. In particular, it highlights the new definitions of spousal abuse and procedures adopted in both criminal and non-criminal courts. The region has seen two countervailing tendencies, the first to criminalise, through penal code definitions and higher penalties, the second to divert this offence into legal arenas that tend, either implicitly or explicitly, towards effective decriminalisation and downgrading of this form of social violence due to their emphasis on conciliation and transactional procedures. This has resulted, in many cases, in a two-track, hybridised treatment of domestic violence that is ultimately unsatisfactory in meeting the various needs of women victims.
The history of the European oil and gas industry reflects local and global political events, economic constraints, and the personal endeavours of individual petroleum geoscientists, as much as it does the development of technologies and the underlying geology of the region. Europe and Europeans played a disproportionately large role in the development of the modern global oil and gas industry. From at least the Iron Age until the 1850s, the use of oil in Europe was limited, and the oil was obtained almost exclusively from surface seeps and mine workings. The use of oil increased in the 1860s with the introduction of new technologies in both production and refining. Shale oil was distilled on a commercial scale in various parts of Europe in the late eighteenth century and throughout the nineteenth century but, in the second half of the nineteenth century, the mineral oils and gas produced primarily from shale and coal could no longer satisfy demand, and oil produced directly from conventional oil fields began to dominate the European market. The first commercial oil wells in Europe were manually dug in Poland in 1853, Romania in 1857, Germany in 1859 and Italy in 1860, before the gradual introduction of mechanical cable drilling rigs started in the early 1860s. In the late nineteenth century, the northern part of the Carpathian Mountains in what is now Poland and Ukraine was one of the most prolific hydrocarbon provinces in the world. The Bóbrka Field in the Carpathian foothills of Poland, discovered in 1853, is still producing and is now the oldest industrial oil field in the world.The 1914–18 and 1939–45 world wars were both major drivers in exploration for and exploitation of Europe's oil resources and in the development of technologies to produce synthetic fuels from the liquefaction of bituminous coal and the combination of carbon monoxide and hydrogen as the Allied and Axis governments struggled to maintain adequate supplies of fuel for their war efforts. In Britain, the first ‘accidental’ discovery of gas was made in 1875 in the Weald Basin, but it was not until 1919 that Britain's first oil field was discovered at Hardstoft, in Derbyshire, as a result of a government-funded exploration drilling campaign, triggered by the need to find indigenous supplies of oil during World War I. The period of reconstruction after World War II was also critical for the European oil and gas industry with further successful exploration for oil and gas in the East Midlands of England resulting in Britain's first ‘oil boom’, and the discovery and development of deep gas fields in the Po Valley in northern Italy fuelling the Italian economy for the next 50 years.Drilling technologies developed during Britain's first oil boom, together with the extrapolation of the onshore geology of the East Midlands oil fields and of the Dutch gas fields, led to the discovery of the huge oil and gas resources beneath the North Sea in the 1960s and 1970s, which enabled Britain, Norway, Denmark and The Netherlands to be largely self-sufficient in oil and gas from the late 1970s until production began to decline rapidly in the early 2000s. Today, oil and gas production in most European countries is at an historical low. Exploration for new sources of oil and gas in Europe continues, although increasingly hampered by the maturity of many of the conventional oil and gas plays, but European companies and European citizens continue to play a major role in the global oil and gas industry.
BackgroundHead and neck cancer (HNC) is the sixth most common cancer worldwide, and the functional, psychological and social consequences of HNC cancer and its treatment can be severe and chronic. Dysphagia (swallowing problems) affects up to two thirds of patients undergoing combined chemoradiotherapy. Recent reviews suggest that prophylactic swallowing exercises may improve a range of short- and long-term outcomes; however, the importance of psychological and behavioural factors on adherence to swallowing exercises has not been adequately studied. This study aims to develop and test the feasibility of a Swallowing intervention Package (SiP) designed in partnership with patients, speech and language therapists (SLTs) and other members of the head and neck multi-disciplinary team (MDT), for patients undergoing chemoradiotherapy (CRT) or radiotherapy (RT) for head and neck cancer.Methods/designThis feasibility study uses quantitative and qualitative research methods, within a quasi-experimental design, to assess whether patients will tolerate and adhere to the SiP intervention, which aspects of the intervention can be implemented and which cannot, whether treatment fidelity can be achieved across different contexts, whether study processes and outcome measures will be feasible and acceptable and to what extent the intervention is likely to have an impact on swallowing dysfunction and quality of life. Patients are being recruited from five sites in Scotland and England (three interventions and two usual care). The SLT based in the relevant intervention centre teaches the exercise programme and provides supporting materials. A combination of patient-reported outcome measures (PROMs), adherence measures and clinical swallowing assessments are used prior to intervention (baseline), at the end of treatment, 3 and 6 months post-treatment.DiscussionThis collaborative study has taken a unique approach to the development of a patient-centred and evidence-based swallowing intervention. The introduction of an e-SiP app provides an exploration of the use of technology in delivering this intervention. The study provides an opportunity to examine the feasibility of delivering and participating in a supported swallowing intervention across several different NHS sites and will provide the evidence needed to refine intervention and study processes for a future trial.Trial registrationNCRI portfolio, 18192 & 20259
This commentary surveys some of the trends and gaps in current research on criminal justice reform in Latin America – with a focus on Brazil, and on two specific areas: police and prison/penal reform. It explores two principal themes: the uneven and thin production of knowledge about criminal justice issues; and the impact this has on policy reforms and on the ways in which these are framed and interpreted in terms of their relative success and failure. Overall it argues that we still know very little about criminal justice institutions and the actors within them. We also need many more finely-grained analyses of the dynamics of reform efforts and of the policy environments in which these take place in order to understand how and why reform initiatives are often derailed or subverted, and, more rarely, flourish and can be embedded and replicated.
No abstract
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
334 Leonard St
Brooklyn, NY 11211
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.