Pseudomonas aeruginosa
is a major pathogen in burn wound infections. We present one of the first reports of small-colony variant (SCV) emergence of
P. aeruginosa
, taken from a patient under aminoglycosides for a persistent burn wound infection. We confirm the causative role of a single
ispA
mutation in SCV emergence and increased aminoglycoside resistance. IspA is involved in the synthesis of ubiquinone, providing a possible link between electron transport and SCV formation in
P. aeruginosa
.
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