Background/aim: We investigated the short-and medium-term effectiveness of genicular nerve radiofrequency (RF) applied in patients with chronic knee pain due to osteoarthritis.
Materials and methods:Radiofrequency was performed in 49 patients with a diagnosis of knee osteoarthritis. VAS and WOMAC were measured at baseline and at 1, 4, and 12 weeks postprocedure. Under fluoroscopic guidance, the cannula was advanced percutaneously towards the area connecting the shaft to the epicondyle. The RF electrode was inserted through the cannula and the electrode tip temperature was raised to 80 °C for 90 s. One RF lesion was made for each genicular nerve.
ObjectivesPreemptive analgesia is a technique in which analgesics are administered before a surgery to provide better postoperative pain relief with fewer side effects. In this study, we aimed to compare the preemptive efficacy of tramadol/acetaminophen fixed-dose combination, tramadol, and acetaminophen in patients undergoing ambulatory arthroscopic partial meniscectomy.MethodsWe evaluated the patient records of 75 patients who underwent ambulatory arthroscopic partial meniscectomy. We divided the patients into three groups consisting of 20 patients each to equalize the groups. Group A comprised patients who were administered 37.5 mg tramadol/325 mg acetaminophen fixed-dose combination, Group B comprised patients who were administered 50 mg tramadol, and Group C comprised patients who were administered 500 mg acetaminophen. Premedication was not used in any group.ResultsThere were no significant differences between the groups in terms of age, sex, BMI, and duration of surgery and anesthesia. All patients in Group B and Group C and 17 patients in Group A required rescue analgesics in the first 6 h. Visual analog scale (VAS) was 4.75 ± 3.05 in Group B at time 0 and was 6.10 ± 1.86 in Group C in the first hour and was higher than the other groups with a statistically significance (p = 0.030 and 0.020, respectively). VAS at 24 h postoperatively was ≤3 (1.60 ± 1.63, 1.55 ± 1.84 and 1.70 ± 0.65 respectively in each group), and none of the patients in any group required rescue analgesics. No major side effects, except for slight nausea in one patient requiring no medication, were noted in any group.ConclusionThe fixed-dose combination of tramadol/acetaminophen or tramadol alone is better than acetaminophen alone as a preemptive analgesic in patients undergoing ambulatory arthroscopic meniscectomy.Level of evidenceLevel III, therapeutic study.
Bu çalışmada sıçanlarda infrarenal abdominal aortun oklüzyonureperfüzyonu sonrası miyokardiyal iskemi reperfüzyon hasarına ozonun etkisi araştırıldı. Ça lış m a pla nı: Otuz iki Wistar albino sıçan (200-250 g ağırlığında) dört eşit gruba randomize edildi. Kontrol (sham) grubunda laparotomi ve oklüzyon olmaksızın infrarenal abdominal aort diseksiyonu uygulandı. Kontrol+ozon grubunda 10 gün 1 mg/kg/gün intraperitoneal ozon uygulandı. Daha sonra, kontrol+ozon grubunda laparotomi ve oklüzyon olmaksızın infrarenal abdominal aort diseksiyonu uygulandı. Aortik iskemi reperfüzyon ve aortik iskemi reperfüzyon+ozon gruplarında infrarenal abdominal aort diseksiyonu uygulandı, takiben infrarenal abdominal aorta 60 dakika krosklemp konularak ve 60 dakika kros-klemp kaldırılarak sırasıyla iskemi ve reperfüzyon gerçekleştirildi. Miyokardiyal örneklerde dokulardaki malondialdehit düzeyleri ve süperoksit dismutaz, katalaz ve myeloperoksidaz aktivite düzeyleri ölçüldü. Plazma tümör nekroz faktörü, interlökin-6 ve troponin-I düzeyleri ölçüldü. Miyokardiyal örneklerin histopatolojik incelemesi yapıldı. Bul gu lar: Biyokimyasal analiz; ozonun doku süperoksit dismutaz ve katalaz düzeylerini ve plazma troponin-I düzeyini anlamlı olarak azaltırken (aortik iskemi reperfüzyona karşı p<0.05) aortik iskemi reperfüzyonun anlamlı olarak artırdığını gösterdi (kontrole karşı p<0.05). Histopatolojik olarak aortik iskemi reperfüzyon grubundaki myokardiyal doku örneklerinde myokardiyal disorganizasyon, myofibriler şişme ve myofibriler eozinofili kontrol grubuna kıyasla anlamlı olarak arttı (kontrole karşı p<0.05). Bununla birlikte, aortik İR+ozon grubunda histopatolojik değişiklikler aortik iskemi reperfüzyon grubuna göre azaldı. So nuç: Bu deneysel çalışmanın sonuçları ozonun infrarenal aortik iskemi reperfüzyon sonrası oluşan miyokardiyal hasarı ve oksidatif stresi üç temel belirteçle azaltabileceğini gösterdi: (i) azalmış doku süperoksit dismutaz ve katalaz düzeyleri, (ii) azalmış plazma troponin-I düzeyleri ve (iii) istatistiksel olarak anlamlı olmamakla beraber azalmış histopatolojik değişiklikler.
Giant ovarian adenomas are rarely observed today because of early diagnosis and treatment. Mucinous cystadenomas is a kind of tumor that mostly causes the ovary to enlarge. Theu can present with various and non-specific clinical manifestations such as deep vein thrombosis. The primary symptoms of giant ovarian tumors are abdominal enlargement and distension. Therefore, making the correct preoperative diagnosis is sometimes difficult. The appropriate treatment must include oncologic procedures and a multidisciplinary approach to minimalize complications and save the patient’s life.Herein, we report a woman aged 53 years with a 27-kg ovarian mucinous cystadenoma that presented as a left popliteal vein thrombosis.
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