Despite the high prevalence and devastating outcome, only a few treatment options for cerebral ischemic stroke exist. Based on the nitric oxide (NO)-stimulating capacity of Non-pulsed Sinusoidal Electromagnetic Field (NP-SEMF) and the possible neuroprotective role of NO in ischemic stroke, we hypothesized that NP-SEMF is able to enhance survival and neurological outcome in a rat model of cerebral ischemia. The animals, in which ischemic injury was induced by occlusion of both common carotid arteries, received 20 min of NP-SEMF of either 10 or 60 Hz daily for 4 days. NP-SEMF dramatically increased survival, reduced the size of the infarcted brain area and significantly improved the neurological score of the surviving rats. Corresponding to previous reports, NP-SEMF was able to induce NO production
in vitro
. The importance of NO as a key signaling molecule was highlighted by inhibition of the NP-SEMF beneficial effects in the rat stroke model after blocking NO synthase (NOS). Our results indicate for the first time that NP-SEMF exposure (13.5 mT at 60 and 10 Hz) improves the survival and neurological outcome of rats subjected to cerebral ischemia and that this effect is mediated by NO, underlining the great therapeutic potential of NP-SEMF as a therapy for ischemic stroke.
La proliferación acelerada de antenas de estaciones base de telefonía celular en el área urbana de las ciudades ha generado una masiva preocupación en la ciudadanía, especialmente de las personas que viven en la vecindad de las estaciones base de telefonía celular, la cual es motivada por los temores acerca de los posibles efectos nocivos de los campos electromagnéticos en la salud. En este trabajo se presentan los resultados de la caracterización del campo electromagnético (CEM) producido en un ambiente urbano por sistemas de comunicación inalámbricos, tales como estaciones base de telefonía celular y antenas de radio y TV. La caracterización se hizo en la vecindad de 26 antenas de la ciudad de Riobamba – Ecuador (en total 168 puntos de medición), utilizando un medidor de campo de banda ancha NARDA NBM 550, operando en el rango de frecuencias desde 100 kHz a 3 GHz. Se registraron los valores máximos de la intensidad del campo eléctrico y la coordenada del Sistema de Posicionamiento Global (GPS) en cada punto medido. Se estudió el cumplimiento con las directrices de la Comisión Internacional sobre Protección frente a Radiaciones No Ionizantes (ICNIRP) y las regulaciones ecuatorianas de seguridad frente al CEM ambiental. Los resultados mostraron que los niveles del campo eléctrico están muy por debajo de los límites establecidos. Sin embargo, debido al crecimiento de la ciudad y al incremento de antenas en el futuro, se recomienda mantener un monitoreo regular en la zona con la finalidad de evaluar la evolución temporal y de estudiar la distribución espacial del ambiente electromagnético.
A filtering of a discrete signal of electric field intensity () in the frequency band from 76 MHz to 2686 MHz is proposed applying the previous moving average with n = 2. The database of temporal measurements of obtained was used. in the continuous monitoring of one day inside the ESPOCH using the NARDA SRM-3000 equipment. The vector of the mean values of the intensity of corresponding to each instant of time, is made up of 240 points because the measurements were obtained every 6 minutes, resulting in a signal of discrete intensity of . To achieve the correct smoothing (filtering) of, the previous moving average algorithm with n = 2 requires 30 passes or iterations. The result that was obtained was a smoother signal compared to the original signal, without the resulting signal losing its original shape.EEEE
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