Better knowledge and understanding about drug desensitization is required in the pediatric population, since there is little literature available about it and the most pediatric desensitization protocols have been adapted from adult instructions.
Aiming to soften this issue and foster the future studies, this article presents a recent review about mechanisms of desensitization, diagnostic tools, and up to date management of drug hypersensitivity reactions in children. Bringing up an overview of pediatric hypersensitivity reactions to chemotherapy, biologic agents, antibiotics, nonsteroidal anti-inflammatory drugs, and vaccines.
A urticária é uma doença frequente que provoca grande impacto na qualidade de vida dos pacientes, principalmente na sua forma crônica. Neste artigo, revisamos a relação entre autoimunidade e urticária: como a autoimunidade está inserida na fisiopatologia das urticárias crônicas, e aspectos relacionados com o diagnóstico diferencial entre urticárias e lesões urticariformes, especialmente aqueles associados às doenças autoimunes e autoinflamatórias. O tratamento atual das urticárias crônicas é abordado no final, de forma prática e concisa.
Unitermos: Urticária. Diagnóstico diferencial. Autoimunidade. Doença autoinflamatória hereditária.
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