Objective To investigate the prevalence of premenstrual syndrome (PMS) and premenstrual dysphoric disorder (PMDD) in university students, the factors associated with PMS, the most prevalent symptoms, and the interference of symptoms in academic, family, social, and work activities. Methods This cross-sectional study included 1,115 university students aged ≥ 18 years from the University of Rio Verde, Goiás. Premenstrual syndrome and PMDD were identified using the Premenstrual Symptoms Screening Tool. Associations with sociodemographic, behavioral, reproductive, nutritional, and health factors were investigated using the Poisson regression. Results The prevalence of PMS was 46.9% (95% confidence interval [CI] 44.0–49.8), and of PMDD, 11.1% (95% CI 9.3–13.0). The most prevalent symptoms were physical, such as breast tenderness, bloating, e weight gain (73%); followed by psychological ones such as overeating/food cravings, tearful/more sensitive to rejection (> 60%). More than 30% of the patients reported that the symptoms interfered in a moderate-to-severe way in their social and academic activities. After adjusted analysis, PMS was more prevalent in those who were attending the 1st/2nd semester of college (prevalence ratio [PR] 1.44; 95% CI 1.14–1.80), those who consumed alcohol in the last 30 days (PR 1.23; 95% CI 1.04–1.47), and those who had depression (PR 1.49; 95% CI 1.30–1.71). Conclusion Almost half of the university students had PMS and ∼ 11%, PMDD. Physical symptoms were the most common and interfered in a moderate-to-severe way in various aspects of life. Attending the first semesters, consuming alcohol, and having depression were risk factors for PMS. The identification of risk factors for PMS is essential to prevent symptoms and reduce the impact of the syndrome.
Para realização deste trabalho foram utilizados 45 camundongos da linhagem C57BI/6, divididos em 2 grupos, sendo o do Grupo I com 30 animais e do Grupo II com 15 animais. Cada animal foi inoculado com IO3 ovos infectantes de Toxocara canis, via ora!, através de uma sonda introduzida diretamente no esõfago. Os ovos utilizados como inoculo foram obtidos por dissecação de exemplares fêmeas do parasito e mantidos em solução formaldeído a 1%, por um período de 40 dias, até a obtenção do estágio infectante. Os animais do Grupo I foram submetidos a tratamento com Albendazol após o 7°d ia de infecção, na dosagem de 400mg/kg/dia, por via oral, durante 30 dias. Os camundongos do Grupo II (grupo controle) não foram tratados com a droga. No 5fl dia após o término do tratamento, todos os animais foram necropsiados sendo examinados cérebro e olhos através da técnica de compressão entre lâminas, ao microscópio óptico. Foi observado nível de eficácia de 76,36%. Concluímos que o esquema terapêutico utilizado neste experimento foi ineficaz no tratamento da Toxocaríase experimental.UNITERMOS: Larva migrans visceral; Toxocara canis; Aibendazol. INTRODUÇÃOA síndrome Larva Migrans Visceral (LMV) foi conceituada por BEAVER como resultado da migração prolongada de certas larvas de helmintos através de tecidos de hospedeiros não habituais, particularmente o homem. As espécies mais comumente envolvidas na génese da LMV são ascarídeos de cães e gatos como Toxocara canis, Toxocara cati, Toxocara leonina.
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