RESUMOO melanoma ungueal é uma forma de apresentação rara do melanoma. É frequente o diagnóstico tardio. Geralmente afeta polegar ou hálux e a maioria dos pacientes é de meia idade ou idosos de pele escura. A associação entre melanoma e vitiligo é tem sido descrita há mais de 50 anos e os pacientes acometidos tem apresentado maior sobrevida sugerindo resposta imune ao melanoma. O objetivo deste relato é descrever um caso de melanoma ungueal com surgimento de linfonodo inguinal e vitiligo associado diagnosticado tardiamente com posterior evolução para doença sistêmica.Palavras-chave: Melanoma. Vitiligo. Doenças da Unha. Recidiva. ABSTRACTSubungual melanoma is a rare clinical entity of melanoma. It usually involves an unsuspecting lesion in the thumb or big toe, thus late diagnosis. Majority of patients are middle-aged or older, usually of dark skin ethnicity. The association between melanoma and vitiligo has been described for over 50 years, showing increased survival rates in affected patients suggesting immune response to melanoma. The objective of this report is to describe a clinical case of nail melanoma, presenting as enlargened unilateral inguinal lymph node associated with rapid and progressive vitiligo. However, investigations proved late diagnosis, with subsequent progression of the disease.
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