Objetivo. Traçar um perfil epidemiológico através da coleta e análise de dados de pacientes com Meningioma Cerebral na região do Alto Tietê. Método. Para esse trabalho foi determinado um intervalo entre janeiro de 2010 a dezembro de 2012. Prontuários da área de neurocirurgia foram solicitados e obteve-se uma amostra de 674 casos. Os prontuários foram selecionados de acordo com as palavras-chave: microcirurgia, microcirurgia de tumor, microcirurgia vascular, microcirurgia para tumor de base de crânio, ressecção de tumor e tratamento conservador de tumor do SNC. Dessa filtragem foram obtidos 90 prontuários que se encaixavam nos quesitos necessários. Estes foram observados e foi constatado um total de 20 prontuários referentes ao Meningioma Cerebral, dos quais foram feitas as análises. Resultados. A doença tem maior incidência em duas situações: em pacientes com mais de 50 anos e em pacientes do sexo feminino. Grande parte dos prontuários analisados mostrou que não houve sequelas e daqueles que apresentaram, o maior índice foi de sequela motora. Conclusões. O perfil epidemiológico do Meningioma no Alto Tietê é de pacientes com 50 anos ou mais, do sexo feminino. A maioria dos pacientes não tem sequelas. Porém nos que apresentaram sequelas, a incidência destas foram predominantemente motora, compreendendo 75% dos casos.
Objective To evaluate the improvement in screening accuracy of the Fracture Risk Assessment Tool (FRAX) for the risk of developing osteoporosis among young postmenopausal women by associating with it clinical muscle mass measures. Methods A sample of postmenopausal women was submitted to calcaneal quantitative ultrasound (QUS), application of the FRAX questionnaire, and screening for the risk of developing sarcopenia at a health fair held in the city of São Bernardo do Campo in 2019. The sample also underwent anthropometric measurements, muscle mass, walking speed and handgrip tests. A major osteoporotic fracture (MOF) risk ≥ 8.5% on the FRAX, a classification of medium risk on the clinical guideline of the National Osteoporosis Guideline Group (NOGG), and a QUS T-score ≤ -1.8 sd were considered risks of having low bone mass, and QUS T-score ≤ -2.5sd, risk of having fractures. Results In total, 198 women were evaluated, with a median age of 64 ± 7.7 years, median body mass index (BMI) of 27.3 ± 5.3 kg/m2 and median QUS T-score of −1.3 ± 1.3 sd. The accuracy of the FRAX with a MOF risk ≥ 8.5% to identify women with T-scores ≤ -1.8 sd was poor, with an area under the curve (AUC) of 0.604 (95% confidence interval [95%CI]: 0.509–0.694) for women under 65 years of age, and of 0.642 (95%CI: 0.571–0.709) when age was not considered. Including data on muscle mass in the statistical analysis led to a significant improvement for the group of women under 65 years of age, with an AUC of 0,705 (95%CI: 0.612–0.786). The ability of the high-risk NOGG tool to identify T-scores ≤ -1.8 sd was limited. Conclusion Clinical muscle mass measurements increased the accuracy of the FRAX to screen for osteoporosis in women aged under 65 years.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.