Titanium (Ti) and Ti-6 Aluminium-4 Vanadium alloys are the most common materials in implants composition but β type alloys are promising biomaterials because they present better mechanical properties. Besides the composition of biomaterial, many factors influence the performance of the biomaterial. For example, porous surface may modify the functional cellular response and accelerate osseointegration. This paper presents in vitro and in vivo evaluations of powder metallurgy-processed porous samples composed by different titanium alloys and pure Ti, aiming to show their potential for biomedical applications. The porous surfaces samples were produced with different designs to in vitro and in vivo tests. Samples were characterized with scanning electron microscopy (SEM), energy dispersive spectroscopy (EDS) and elastic modulus analyses. Osteogenic cells from newborn rat calvaria were plated on discs of different materials: G1—commercially pure Ti group (CpTi); G2—Ti-6Al-4V alloy; G3—Ti-13 Niobium-13 Zirconium alloy; G4—Ti-35 Niobium alloy; G5—Ti-35 Niobium-7 Zirconium-5 Tantalum alloy. Cell adhesion and viability, total protein content, alkaline phosphatase activity, mineralization nodules and gene expression (alkaline phosphatase, Runx-2, osteocalcin and osteopontin) were assessed. After 2 and 4 weeks of implantation in rabbit tibia, bone ingrowth was analyzed using micro-computed tomography (μCT). EDS analysis confirmed the material production of each group. Metallographic and SEM analysis revealed interconnected pores, with mean pore size of 99,5μm and mean porosity of 42%, without significant difference among the groups (p>0.05). The elastic modulus values did not exhibit difference among the groups (p>0.05). Experimental alloys demonstrated better results than CpTi and Ti-6Al-4V, in gene expression and cytokines analysis, especially in early experimental periods. In conclusion, our data suggests that the experimental alloys can be used for biomedical application since they contributed to excellent cellular behavior and osseointegration besides presenting lower elastic modulus.
<pre><strong>Objective:</strong> To evaluate the visual perception of surface gloss of resin composite under different illuminants by different observers. <strong>Material and methods:</strong> twelve cylindrical specimens (6mm x 1mm) were fabricated using a nanofilled resin composite (Z350, A2E shade) in order to compare different observers and to determine the limit of perceptibility of surface gloss. Bovine tooth specimen with similar dimensions was obtained for the comparison of different illuminants. Polishing of resin specimens was performed resulting in 6 groups, presenting surface gloss values at 10, 25, 40, 55, 70, and 85 GU (gloss units), measured by glossmeter (NOVOCURVE). Fifteen individuals were selected: 5 lay-person, 5 undergraduate students, and 5 dental professionals. Participants observed the specimens in a light booth (Gti lightbox) under three different illuminants, and rated the possible combinations between resin specimens or with the bovine enamel specimen (85GU). Data obtained were analyzed by PROBIT non-linear regression analysis (α=0.05). <strong>Results:</strong> Differences were observed among types of illuminants (p=0.042) and ΔGU (p=0.004), with no interaction between factors (p=0.139). The fluorescent light presented lower surface gloss perceptibility values in relation to incandescent light. There was no influence by type of observers (p =0.598). The surface gloss perception limit was 17.6 GU under the presented tested conditions. <strong>Conclusion:</strong> the illuminant type influenced perception of gloss, with lower percentage of perceptibility for fluorescent light, while such perceptibility was not influence by different observers. </pre><p class="PadroAA"><strong>Keywords</strong><strong></strong></p><p class="PadroAA"> Illuminants; Observer variation; Composite resins; Surface gloss.</p>
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