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Background Leptin in breast milk play a significant role in metabolic programming. Objective The aim of this study to evaluate the relationship between leptin levels in maternal serum and breast milk, and certain anthropometric measurements of infants and mothers. Methods This study was conducted with 65 females and term infants. Anthropometric measurements of the mothers and the infants were obtained on the first, third, and sixth months, and leptin levels in maternal serum and breast milk were measured. Results In this study, leptin levels in breast milk were positively correlated with leptin levels in maternal serum while the leptin levels in breast milk were lower than the serum leptin levels. It was also determined that mothers’ body weights, BMI values, waist and hip circumferences were increased in a statistically significant way in terms of the months ( p < .001). It was discovered that all the anthropometric measurements of the mothers were positively correlated with leptin levels in breast milk and maternal serum in all the months ( p < .001). Furthermore, it was determined that the body weights of the infants in certain months were negatively correlated with leptin levels in breast milk and maternal serum while the lengths of the infants were positively correlated with leptin levels in breast milk and maternal serum ( p < .05). Conclusions This study was determined that leptin levels in breast milk and maternal serum were related to anthropometric measurements of both mothers and infants. Future studies with larger populations are needed to understand the long-term consequences of leptin metabolism comprehensively. Key messages This study was determined that breast milk leptin level and maternal serum leptin level demonstrated a positive correlation, and breast milk leptin level was lower than maternal serum leptin level. Mothers' anthropometric measurements were positively correlated with leptin levels in breast milk and maternal serum in all the months. There was mostly a negative correlation between breast milk leptin level and infant body weight.

Objectives There is limited evidence about the inflammatory potential of diet and cardiometabolic risk in children. The aim of this study was to evaluate the association between the Children’s Dietary Inflammatory Index (C-DII) with cardiometabolic risk factors in Turkish adolescents from 10 to 17 years. Methods Participants aged 10–17 years, who completed a 24-h dietary recall, from which C-DII scores were calculated, were include in this cross-sectional study. Lipid profile, glycemic parameters, high-sensitivity C-reactive protein (hs-CRP), liver enzymes, thyroid-stimulating hormone (TSH), and uric acid were analyzed in blood samples. Sociodemographic characteristics and sedentary behavior were assessed using a semi-structured questionnaire. We compared the distributions of anthropometric, biochemical, and blood pressure measurement levels associated with cardiometabolic risk factors by the median of C-DII with linear regression. Results The mean sample C-DII was −0.16 ± 2.31 and ranged from −3.22 to +4.09. Higher median C-DII scores, indicating a more pro-inflammatory diet among children, were associated with higher blood pressure and body mass index (BMI). However, the C-DII was modestly directly associated with fasting insulin, fasting blood glucose, and waist circumference. The area under the receiver operating curve of C-DII in predicting hs-CRP was found to be quite high (0.864, 95% CI: 0.795–0.933). Conclusions Consuming a pro-inflammatory diet in adolescence was associated with alterations in cardiometabolic risk factors, especially with systolic blood pressure, diastolic blood pressure, and BMI.

Purpose: To adapt and validate the an abbreviated version of the Mindful Eating Questionnaire (MEQ-18) to the Turkish language for a Turkish adult population.Methods: This cross-sectional study included 709 participants aged between 18-65 years living in the province of Elazig. The data was collected through a voluntary face-to-face survey. The questionnaire was included their general characteristics and the MEQ-18 and Eating Attitude Test-26 (EAT-26). Confirmatory factor analysis (CFA) was used to test the validity of the MEQ-18. Statistical analyzes were conducted using the R-Project program and IBM SPSS Statistics for Windows 26.0.Results: The overall content validity index was 0.93. A confirmatory factor analysis was conducted for the two sub-scales and reduced the abbreviated of MEQ to 18 items. The Cronbach’s alpha coefficient was 0.718 for the MEQ-18 total factor scores and Cronbach alpha values for awareness, and disinhibition were found to be 0,843 and 0,789, respectively. The minimum discrepancy per degree of freedom = 4.914 and the model generally fit well to the structure (RMSEA = 0.074, CFI = 0.934, SRMR = 0.079, TLI = 0.925, GFI = 0.968, AGFI = 0.959).Conclusions: The findings of study showed that the psychometric properties of the abbreviated MEQ adapted into Turkish were acceptable through construct and internal consistency reliability.Level of evidence: Level V, descriptive cross-sectional study.

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ÖZET Amaç: Dünyada ve ülkemizde böbrek hastalarının sayısı gittikçe artmaktadır. Tedavideki gelişmelere rağmen bu hasta grubunda mortalite hâlâ yüksektir. Mortaliteyi etkileyen faktörlerin başında protein enerji malnütrisyonunun ve buna bağlı olarak gelişen inflamasyonun geldiği artık bilinmektedir. Bu kesitsel çalışma ile kronik böbrek hastalarının beslenme durumları ve malnütrisyon inflamasyon skorlarının belirlenmesi amaçlanmaktadır. Gereç ve Yöntemler: Bu çalışmada, Fırat Üniversitesi Hastanesi Nefroloji Kliniğine ve Elazığ ilinde bulunan özel bir diyaliz merkezine başvuran 18-65 yaş arası 70 hasta incelenmiştir. Hastaların sosyodemografik özellikleri, beslenme alışkanlıkları ve fiziksel aktivite durumları anket formu yöntemi ile besin tüketim kayıtları ise 24 saatlik hatırlatma yöntemi ile alınmıştır. Hastaların antropometrik ölçümleri araştırmacılar tarafından kayıt edilmiştir. Ayrıca hastalara malnütrisyon inflamasyon skoru (MİS) ölçeği uygulanmıştır. Bulgular: Yaş ortalamaları 50,8±13,4 yıl olan hastaların ortalama MİS'lerinin 8,3±4,7 ve %61,4'ünün malnütrisyonlu olduğu bulunmuştur. Malnütrisyonlu hastaların vücut ağırlığının, boy uzunluğunun, beden kitle indeksi değerlerinin, bel, kalça ve üst orta kol çevrelerinin, malnütrisyonlu olmayan hastalara kıyasla daha düşük olduğu belirlenmiştir (p<0,05). Ayrıca malnütrisyonlu hastaların C-reaktif protein, kreatinin, üre, sodyum ve inorganik fosfor düzeyleri, malnütrisyonlu olmayan hastalara oranla daha yüksek bulunurken, glomerül filtrasyon hızı düzeyleri daha düşük bulunmuştur (p<0,05). Hastaların beslenme durumları değerlendirildiğinde her iki grup arasında istatistiksel olarak anlamlı bir fark saptanmamıştır (p>0,05). Sonuç: MİS ile hastaların antropometrik ölçümleri ve bazı kan parametreleri arasında doğrusal bir ilişki olması sebebiyle MİS'in kronik böbrek hastalarında kullanılması doğru bir yaklaşım olacaktır. Bu çalışmada, beslenme durumu ve MİS arasında istatistiksel olarak anlamlı bir ilişki bulunmamıştır. Beslenme durumunun MİS ile arasındaki ilişkinin daha iyi anlaşılabilmesi için geniş kapsamlı çalışmaların yapılması önerilmektedir.Anah tar Ke li me ler: Kronik böbrek hastalığı; beslenme; malnütrisyon inflamasyon skoru; malnütrisyon; inflamasyon ABS TRACT Objective:The number of kidney patients is increasing in the world and in our country. Despite advances in treatment, mortality is still high in this patient group. It is now known that protein energy malnutrition and associated inflammation are the leading factors affecting mortality. With this cross-sectional study, it is aimed to determine the nutritional status and malnutrition inflammation scores of patients with chronic kidney disease. Material and Methods:In this study, 70 patients between the ages of 18-65 who applied to Fırat University Hospital Nephrology Clinic and a private dialysis center in Elazığ were examined. Sociodemographic characteristics, nutritional habits and physical activity status of the patients were obtained with the questionnaire method, and food consumption records we...

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