The objective of this work is to present longterm results of valve replacement using SJM-Biocor TM bovine pericardial bioprostheses. Methods: From 1992 to 2000, 304 patients were discharged from hospital after bioprosthesis implantation. Ages ranged from 15 to 83 years (mean: 60.6 ± ± ± ± ± 14.3 years) and 50.3% were male. Patient deaths and events related to bioprosthesis (infection, thromboembolism and structural failure) were considered for estimation of cumulative probability of survival and event-free survival. Results: Total follow-up was 931.0 patients-year. During follow-up there were 28 (9.2%) deaths. Causes were bioprosthesis failure in five (1.6%), cardiac in seven (2.3%), non-cardiac in four (1.3%), and unknown in 12 (3.9%) patients. Events related to bioprosthesis were: endocarditis: 18 (5.9%), fibrocalcific degeneration: 15 (4.9%), thromboembolism: three (1.0%), hemolysis: one (0.3%). Bioprosthesis dysfunctions resulted in 16 (5.2%) reoperations due to fibrocalcific degeneration (nine), endocarditis (six) and thromboembolism (one). Probability of survival was higher in the young population (< 40 years, n=35) when compared to the older group (> 60 year, n=187): 82.0 ± ± ± ± ± 13.3% vs. 58.8 ± ± ± ± ± 13.6% in the 9 th year. Event-free survival was 77.5 ± ± ± ± ± 3.7% for 5 th year and 40.2 ± ± ± ± ± 9.0% for 10 th year. Overall estimative of structural failure for a SJM-Biocor TM was 5% in 5 th year increasing to 20% in the 10 th year. In the aortic position the values were zero and 8%, respectively. Considering current clinical conditions, 88.5% are in NYHA class I, 9.1% in class II and 2.3% in class III. Conclusions: SJM-Biocor TM bovine pericardial bioprostheses resulted in satisfactory survival of patients, related to low prevalence of bioprosthesis dysfunction. Descriptors: Bioprosthesis. Heart valve prosthesis. Heart valves. Resumo Objetivo: Nosso objetivo é apresentar resultados a longo prazo da subsituição valvar por bioprótese de pericárdio bovino SJM-Biocor TM. Método: Entre 1992 e 2000, tiveram alta hospitalar, após substituição valvar por bioprótese de pericárdio bovino SJM-Biocor TM 304 pacientes. Idades eram de 15 a 83 anos (média: 60,6± ± ± ± ±14,3), sendo 50,3% do sexo masculino. Pacientes tiveram situação clínica atualizada e análise atuarial foi empregada no cálculo da sobrevida simples e livre de eventos.