second primary cancer. review of 196 cases Background: A second primary cancer is that occurring in patients who have survived a previous cancer and its frequency is 16%. aim: To identify and characterize patients with a second primary cancer treated in a clinical hospital. material and methods: Review of the database of the Clinical Oncology Unit of a surgical department between 2004 and 2012. Among 4,007 patients operated for cancer, 196 (mean age 63 years, 51% women) had a previous history of cancer, whose medical records were reviewed. results: In the study period the frequency of a second primary cancer in endocrinological, thoracic and digestive surgery was 4.9%. There was a mean lapse of 8.2 years between the first and second cancer and 24% of patients had a family history of cancer. The second primary lesions were located in colon in 26%, stomach in 19%, thyroid in 16%, rectum in 12%, pancreas in 8% and lung in 8%. Sixty five percent of lesions was diagnosed in stage IV with peritoneal and lung metastases in 38 and 25% respectively. conclusions: Second primary cancer is uncommon in this series. The high frequency of colon cancer must be highlighted. Due to the lapse between the first and second tumor, follow up of patients treated for cancer should be maintained for at least eight years.
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