This paper investigates market reaction to the novel corona virus (COVID-19) pandemic. Using a sample of Chinese listed firms, we find that market reaction to the COVID-19 outbreak is more intense in firms within the industries that are vulnerable to the virus, and those with high institutional investors. Furthermore, firms with larger scale, better profitability and growth opportunity, higher combined leverage, and less fixed assets experience less adverse impact of the COVID-19 outbreak than other firms.
Autism spectrum disorder (ASD) has complex neurodevelopmental impairments and origins that are linked to both genetic and environmental factors. Hence, there is an urgency to establish animal models with ASD-like characteristics to understand the underlying mechanisms of ASD. Prenatal exposure to valproic acid (VPA) produced ASD-like symptoms in humans, rats, and recently zebrafish. The present study investigated the use of VPA exposure to generate an ASD model in zebrafish. Early life stage exposures produced ASD-like phenotypes in the developing brain development and behavioral changes in embryonic and larval zebrafish. Our findings revealed that treating zebrafish embryos with VPA starting at 8h post fertilization (hpf) resulted in significant: increase in the ASD macrocephalic phenotype; hyperactivity of embryo/larvae movement behaviors; and increases of ASD-like larval social behaviors. Further analysis showed increases in cell proliferation, the proportion of mature newborn neurons, and neural stem cell proliferation in the brain region, which may contribute to the brain overgrowth and macrocephaly observed following VPA exposure. Our study demonstrated that VPA exposure generates ASD-like phenotypes and behaviors, indicating that zebrafish is an alternative model to investigate underlying ASD mechanisms.
CuPd nanocrystals with different shapes including cubes, truncated cubes, cuboctahedra, irregular polyhedra, and tetrapods, have been synthesized by the modification of reactant concentrations. The electrocatalytic activity of the CuPd nanocubes toward the oxygen reduction reaction (ORR) is the higher than the commercial Pt/C catalyst.
Although the entrepreneurial intention of university students has been studied from different perspectives, the results are still not convergent, and the mechanism and outcomes related to how entrepreneurial intention could be affected by different factors lacking integrated investigation and comparative research. Based on emotional theory, the theory of planned behavior (TPB), and entrepreneurial cognitive theory, as well as the perception of specific situations encountered by university students, this paper attempts to explore entrepreneurial intention from three perspectives, including individual, family and school; and constructs an integrated model that includes entrepreneurial passion, role models, entrepreneurial education, entrepreneurial self-efficacy, and entrepreneurial intention. Based on a survey of university students in the Pearl River Delta of China, this paper attempts to explore the intrinsic mechanism of the development of entrepreneurial intention from these three perspectives. The results show that entrepreneurial passion, role models, and entrepreneurial education could have different effects on entrepreneurial intention; additionally, entrepreneurial self-efficacy plays an important mediating role. The research findings contribute to the literatures regarding the factors influencing entrepreneurial intention, providing empirical evidence to formulate policies to encourage university students’ entrepreneurship practices and help to enhance effectiveness of entrepreneurship education.
This paper investigates market reaction to the novel corona virus (COVID-19) pandemic. Using a sample of Chinese listed firms, we find that market reaction to the COVID-19 outbreak is more intense in firms within the industries that are vulnerable to the virus, and those with high institutional investors. Furthermore, firms with larger scale, better profitability and growth opportunity, higher combined leverage, and less fixed assets experience less adverse impact of the COVID-19 outbreak than other firms.
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