A diluted 3% w/w hydrogen peroxide solution acidified to pH 2.5 by adding citric acid
inactivated SARS-CoV-2 virus by more than 4 orders of magnitude in 5 min. After a
contact time of 15 min, no viral replication was detected. Aqueous solutions of sodium
percarbonate inactivated coronavirus by >3 log
10
diminution in 15 min.
Conversely, H
2
O
2
solutions with no additives displayed a scarce
virucidal activity (1.1 log
10
diminution in 5 min), confirming that a
pH-modifying ingredient is necessary to have a H
2
O
2
-based
disinfectant active against the novel coronavirus.
This is a PDF file of an article that has undergone enhancements after acceptance, such as the addition of a cover page and metadata, and formatting for readability, but it is not yet the definitive version of record. This version will undergo additional copyediting, typesetting and review before it is published in its final form, but we are providing this version to give early visibility of the article. Please note that, during the production process, errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.