No abstract

Application of DPSCs significantly improved clinical parameters of periodontal regeneration 1 year after treatment.

The presence of periodontal bacteria in atheromatous plaques was not confirmed by this investigation; thus, no correlation could be drawn between periodontitis bacteria and microorganisms involved in the atherosclerotic lesions.

Periodontitis was highly prevalent in the Turin population. The present data will enable development of appropriate public health programs and allocation of resources.

Alveolar sockets with extensive buccal bone deficiencies undergo significant three-dimensional volumetric alterations following natural healing. The immediate application of a slow-resorbing xenograft with a covering collagen membrane seems to be effective in improving alveolar ridge shape and dimensions, thus potentially reducing the need for adjunctive regenerative procedures at the time of implant placement.

Objectives Due to the inconclusive findings on the effect of laser therapy in the management of peri‐implant diseases, the aim of this study was to analyze the adjunctive clinical efficacy of 980‐nm diode laser (DL) irradiation in the treatment of peri‐implant mucositis with mechanical debridement. Material and methods Two hundred and twenty patients with one implant diagnosed with peri‐implant mucositis (probing depth [PD] ≥ 4 mm and bleeding on probing [BoP] [primary outcome]) were randomly allocated to test and control treatments. Patients in the control group (n = 110) received debridement using curettes and ultrasonic devices, while patients allocated in the test group (n = 110) received mechanical therapy in combination with DL irradiation (setting 980 nm, 2.5 W, 10 kHz, pw, 30 s). BoP, presence of plaque, and PD were recorded at baseline, 1 month, and 3 months after treatment. Results Both therapeutic modalities yielded similar clinical improvements with comparable reductions in the number of BoP‐positive sites, plaque scores, and PD values at 3 months (all p‐values > 0.05). Complete disease resolution was obtained in 38/110 (34.5%) implants in the test group compared with 34/110 (30.9%) implants in the control group at the end of the observation period. Conclusion Based on these results, the adjunct use of DL did not yield any statistically significant clinical benefit as compared to nonsurgical mechanical treatment alone in controlling peri‐implant inflammation at 3 months.

The use of EMD as an adjunct to non-surgical periodontal treatment may be considered a suitable option to treat defects mainly in the anterior sextants.

Although the periodontal therapy successfully decreased clinical signs of inflammation, the GCF levels of some inflammatory cytokines were still elevated.