Monoamine oxidase (MAO) inhibitors are generally used in the treatment of depressive disorders and some neurodegenerative illnesses, such as Parkinson's disease and Alzheimer's disease. The aim of this preliminary study was to investigate the MAO [MAO (E.C.1.4.3.4)] inhibiting effect of various apitherapeutic products, such as chestnut honey, pollen and propolis. Extracts' MAO inhibition was measured using peroxidase-linked spectrophotometric assay in enzyme isolated from rat liver microsomes, and the values are expressed as the inhibition concentration (IC 50 ) causing 50% inhibition of MAO. The antioxidant activity of the bee products was also determined in terms of total phenolic content (TPC) and ferric reducing/ antioxidant power in aquatic extracts. All samples exhibited substantial inhibition of MAO, propolis having the highest. Inhibition was related to samples' TPCs and antioxidant capacities. These results show that bee products possess a sedative effect and may be effective in protecting humans against depression and similar diseases.
Polyphenols are important secondary products of plants with the potential to inhibit carbonic anhydrases. The aim of this study was to investigate the inhibition effects of various phenolic standards, honey, propolis, and pollen species on human carbonic anhydrase I and II. The inhibition values (IC 50 ) of the phenolics (gallic acid, protocatechuic acid, quercetin, catechin, tannic acid, and chrysin) ranged from 0.009 to 0.32 mg/mL, tannic acid emerging as the best inhibitor. The inhibition values of three different types of honey, heather, rhododendron, and chestnut ranged between 2.32 and 25.10 mg/mL, the chestnut honeys exhibiting the best inhibition. The ethanolic extracts of pollen and propolis exhibited good inhibitory properties, with IC 50 values between 0.486 and 3.320 mg/mL. In order to evaluate the phenolic composition of bee products, phenolic profiles and total phenolic contents (TFC) were also measured. The inhibition ranking among the natural products studied was phenolic standards4prop-olis4pollen4honeys, and inhibition was related to TFC.
Arı sütü binlerce çiçekten özümsenen nektar ve çiçek polenleri ile bal arılarının enzimlerini de içeren, akıcı jel halinde ve kremsi-beyaz renkteki etkili bir salgıdır. Besin değeri yüksek bu ürün amino asit, peptit, protein ve minerallerden oluşur. Arı sütünün en önemli özelliği diğer arı ürünlerinde bulunmayan kısa zincirli hidroksi yağ asitlerince zengin oluşudur. Antibakteriyel, anti-tümoral, ve immün sistemi uyarıcı özelliğe sahip arı sütünün majör yağ asidi trans-10-hidroksi-2-dekanoik asit (10-HDA)'dır. Yapılan bu çalışma ile farklı yıllarda toplanan arı sütü örneklerinin nem ve 10-HDA miktarı tayin edildi. HPLC-UV ile ölçülen 10-HDA miktarının yıllara göre ortalama %2.1 ile %2.6 arasında değiştiği tespit edildi. Arı sütü nem içeriğinin ise ortalama %62.6 ile %66.5 arasında değiştiği tespit edildi.
Özet Tea is one of the most preferred beverages in the world, following water. The content of the tea consists of bioactive polyphenols, especially catechins, which play acrucial role in the quality of tea and human health.
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