A brain–computer interface (BCI) can be used for people with severe physical disabilities such as ALS or amyotrophic lateral sclerosis. BCI can allow these individuals to communicate again by creating a new communication channel directly from the brain to an output device. BCI technology can allow paralyzed people to share their intent with others, and thereby demonstrate that direct communication from the brain to the external world is possible and that it might serve useful functions. BCI systems include machine learning algorithms (MLAs). Their performance depends on the feature extraction and classification techniques employed. In this paper, we propose a system to exploit the P300 signal in the brain, a positive deflection in event-related potentials. The P300 signal can be incorporated into a spelling device. There are two benefits behind this kind of research. First of all, this work presents the research status and the advantages of communication via a BCI system, especially the P300 BCI system for disordered people, and the related literature review is presented. Secondly, the paper discusses the performance of different machine learning algorithms. Two different datasets are presented: the first dataset 2004 and the second dataset 2019. A preprocessing step is introduced to the subjects in both datasets first to extract the important features before applying the proposed machine learning methods: linear discriminant analysis (LDA I and LDA II), support vector machine (SVM I, SVM II, SVM III, and SVM IV), linear regression (LREG), Bayesian linear discriminant analysis (BLDA), and twin support vector machine (TSVM). By comparing the performance of the different machine learning systems, in the first dataset it is found that BLDA and SVMIV classifiers yield the highest performance for both subjects “A” and “B”. BLDA yields 98% and 66% for 15th and 5th sequences, respectively, whereas SVMIV yields 98% and 54.4% for 15th and 5th sequences, respectively. While in the second dataset, it is obvious that BLDA classifier yields the highest performance for both subjects “1” and “2”, it achieves 90.115%. The paper summarizes the P300 BCI system for the two introduced datasets. It discusses the proposed system, compares the classification methods performances, and considers some aspects for the future work to be handled. The results show high accuracy and less computational time which makes the system more applicable for online applications.
DNA microarray is a powerful tool and is widely used in genetics to monitor expression levels of thousands of genes in parallel. The gene expression process consists of three stages: gridding, segmentation and quantification. Gridding deals with finding areas in the microarray image which contain one spot using grid lines. This step can be done manually or automatically. In this paper, we propose an efficient and simple automatic gridding method for microarray image analysis. This method was implemented using MATLAB software and found very effective for gridding arrays with low intensity, poor quality spotsand tested by a number of microarray images. Results show that this method gives high accuracy of 76.9% improved to 98.6% when a preprocessing step is considered, rendering the method a promising technique for an efficient and automatic gridding the noisy microarray images.
Some of the most common blinding conditions are caused by choroidal neovascularization (CNV). The relevant conditions include diabetic retinopathy and age-related macular degeneration. At present, the only proven modality of effective treatment is the application of laser energy to the CNV to cauterize the vessels. The key to effective and lasting treatment is the identification of the full extent of the CNV, cauterization of the CNV completely by accurately aiming an appropriate amount of optical energy while ensuring that healthy tissue is not cauterized. Extraction techniques must be developed to discern the retinal blood vessels tree and determine the positions of laser shots in a reference frame. After extracting the blood vessels tree & determining the locations of the laser shots, those locations will be saved in a database. Due to the eye movement the locations of the laser shots will differ. So, registration of the translation between the reference & the sub-sequent frame in different types of retinal images is required. This paper presents a comparison of two different methods to register blood vessels, which are a prominent retinal structure, in both gray-scale and color retinal images. The blood vessel registration is composed of two algorithms, i.e., registering the blood vessel using Normalized 2-D Correlation algorithm and Minimum Error Function algorithm. Results on various retinal images verify the effectiveness of the proposed methods.
Driver fatigue detection system aims to monitor the driver state. When detecting a fatigue caused by different attitudes other than normal driving habit, the system warns the driver that traveling should be interrupted. In this way, it helps the driver to make the right decision. The aim of this study is to prevent traffic accidents. The system analyzes any changes in the driver's eyes and mouth features in real time and warns the driver when necessary. The proposed system contains several stages to detect the driver's fatigue. First, the preprocessing stage; enhancement of the frames, determining the face, and cropping eyes and mouth of the driver was done. Then, dealing with feature extraction stage; the features concerning each frame was processed. Finally, two classification approaches were presented and a comparison between them was addressed. In the first approach, four traditional classifiers were applied; Diagonal Linear Discriminant Analysis (DiagLDA), Linear Support Vector Machine (LSVM), K-Nearest Neighbor (KNN), and Random Forest Classifier (RFC). The results show that two classifiers; KNN and RFC yield the highest average accuracy of 91.94% for all subjects presented in this paper. In the second approach, one model of deep learning neural network (CNN) was applied; "Resnet-50" model. The results also show that the proposed deep learning model yields a high average accuracy of 96.3889% for the same data. In general, the drowsiness and lost focus of drivers with high accuracy have been detected with the developed image processing based system, which makes it practicable and reliable for real-time applications.
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