Early detection of vessels from fundus images can effectively prevent the permanent retinal damages caused by retinopathies such as glaucoma, hyperextension, and diabetes. Concerning the red color of both retinal vessels and background and the vessel's morphological variations, the current vessel detection methodologies fail to segment thin vessels and discriminate them in the regions where permanent retinopathies mainly occur. This research aims to suggest a novel approach to take the benefit of both traditional template-matching methods with recent deep learning (DL) solutions. These two methods are combined in which the response of a Cauchy matched filter is used to replace the noisy red channel of the fundus images. Consequently, a U-shaped fully connected convolutional neural network (U-net) is employed to train end-to-end segmentation of pixels into vessel and background classes. Each preprocessed image is divided into several patches to provide enough training images and speed up the training per each instance. The DRIVE public database has been analyzed to test the proposed method, and metrics such as Accuracy, Precision, Sensitivity and Specificity have been measured for evaluation. The evaluation indicates that the average extraction accuracy of the proposed model is 0.9640 on the employed dataset.

Intracavity absorption spectroscopy is a strikingly sensitive technique that has been integrated with a two-wavelength setup to develop a sensor for human breath. Various factors are considered in such a scenario, out of which Relative Intensity Noise (RIN) has been exploited as an important parameter to characterize and calibrate the said setup. During the performance of an electrical based assessment arrangement which has been developed in the laboratory as an alternative to the expensive Agilent setup, the optical amplifier plays a pivotal role in its development and operation, along with other components and their significance. Therefore, the investigation and technical analysis of the amplifier in the system has been explored in detail. The algorithm developed for the automatic measurements of the system has been effectively deployed in terms of the laser's performance. With this in perspective, a frequency dependent calibration has been pursued in depth with this scheme which enhances the sensor's efficiency in terms of its sensitivity. In this way, our investigation helps us in a better understanding and implementation perspective of the proposed system, as the outcomes of our analysis adds to the precision and accuracy of the entire system.

Alzheimer’s disease (AD), the most familiar type of dementia, is a severe concern in modern healthcare. Around 5.5 million people aged 65 and above have AD, and it is the sixth leading cause of mortality in the US. AD is an irreversible, degenerative brain disorder characterized by a loss of cognitive function and has no proven cure. Deep learning techniques have gained popularity in recent years, particularly in the domains of natural language processing and computer vision. Since 2014, these techniques have begun to achieve substantial consideration in AD diagnosis research, and the number of papers published in this arena is rising drastically. Deep learning techniques have been reported to be more accurate for AD diagnosis in comparison to conventional machine learning models. Motivated to explore the potential of deep learning in AD diagnosis, this study reviews the current state-of-the-art in AD diagnosis using deep learning. We summarize the most recent trends and findings using a thorough literature review. The study also explores the different biomarkers and datasets for AD diagnosis. Even though deep learning has shown promise in AD diagnosis, there are still several challenges that need to be addressed.

The development of a biomedical sensor involves an extremely sensitive optoelectronics system whose foundations lie on intracavity absoprtion spectroscopy. In order to make it convenient for technical reasons to use this application based utility, we implement dual mode competition. All of the components in this system must be investigated in detail. This work concerns with the design of the optical receiver which is mandatory to understand and analyze the received signal. This has been effectively done by designing an inexpensive system which replaces the existing Agilent based setup. Next, the performance of the system has been investigated by using an important parameter Relative Intensity Noise (RIN). The variation of injection current and temperature and their subsequent effect on RIN has been comprehensively examined. This has been enhanced by an investigation of RIN as subject to the mode positions (values of wavelengths) at which the framework is being operated. Through these considerations, the system's behaviour is understood in a much better way as they lead to an improvement in the sensor's realization with high sensitivity and stability.

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In recent decades, the traffic on road increased in a huge number. It is very important to manage the safety of the humans as well as to make an efficient flow of the traffic. To manage the traffic flow and to overcome from the situation of the traffic congestion the vehicle detection and counting needs a greater amount of accuracy. In this work, two different techniques are proposed that provides better performance in terms of F-Measure score and Error Ratio. The first technique is based on the foreground estimation while the second proposed technique is based on the training of dataset using a cascade classifier which is based on the Histogram of Oriented Gradients (HOG). Furthermore, four images are provided at once to the proposed system to count the vehicles and generate a signal that shows a greater number of vehicles in that image. The priority of each image will be set on the basics of greater number of vehicles present. The proposed techniques showed outstanding performance on a sunny and a cloudy day which is verified from the experimental results.

Voice-driven devices (VDDs) like Google Home and Amazon Alexa, which are well-known connected devices in consumer IoT, have applications in various domains i.e., home appliances automation, next-generation vehicles, voice banking, and so on. However, these VDDs that are based on automatic speaker verification systems (ASVs) are vulnerable to voice based logical access (LA) attacks like Text-to-Speech (TTS) synthesis and converted voice signals. Intruders can exploit these attacks to bypass the security of such systems and gain access of victim's bank account or home control. Thus, there exists a need to develop an effective voice spoofing countermeasure that can reliably be used to protect these VDDs against such malicious attacks. This work presents a novel audio features descriptor named as extended local ternary pattern (ELTP) to capture the vocal tract dynamically induced attributes of bonafide speech and algorithmic artifacts in synthetic and converted speeches. We fused our novel ELTP features with the linear frequency cepstral coefficients (LFCC) to further strengthen the capability of our features for capturing the traits of bonafide and spoofed signals. We employ the proposed ELTP-LFCC features to train the deep bidirectional Long Short-Term Memory (DBiLSTM) network for classification of the bonafide and spoof signal (i.e., TTS synthesis, converted speech). Performance of our spoofing countermeasure is measured on the large-scale and diverse ASVspoof 2019 logical access dataset. Experimental results demonstrate that the proposed audio spoofing countermeasure can reliably be used to detect the LA spoofing attacks.INDEX TERMS Extended local ternary pattern, Logical access attacks, Text-to-speech synthesis, Voice spoofing countermeasure, Voice conversion.

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