10.30699/jambs.29.135.238 Background & Objective: In December 2019, the outbreak of coronavirus disease 2019 (COVID-19) was observed in China, and it it spread rapidly throughout the world. Iranian traditional healers have applied different medicinal plants to prevent and treat COVID-19 based on their ethnopharmacological knowledge. This research aimed to investigate the ethnomedicinal knowledge of Iranian traditional healers to alleviate COVID-19 signs and symptoms. Materials & Methods: Due to the limitations caused by COVID-19 pandemic, oral interviews were conducted by 26 traditional healers in Kerman and Zahedan cities in Iran. The names of recommended remedies for COVID-19 were collected, and their scientific names were authenticated. Next, a comprehensive research was carried out in the scientific databases. Finally, the herbs with any related proved properties to the respiratory system were listed; these herbs were probably useful for the COVID-19 prevention or treatment. Results: Zataria multiflora, Althaea officinalis, Hordeum vulgare, Malva sylvestris, Matricaria chamomilla, Glycyrrhiza glabra, Allium sativum and Zingiber officinale are considered as the most popular herbs by Iranian traditional healers for prevention and/or treatment of COVID-19. Recent studies have demonstrated that the abovementioned herbs can be considered as good sources for alleviating the respiratory disorders such as influenza. Moreover, they have antitussive and immune-modulatory properties.
Conclusion:Since there is no effective treatment for COVID-19, the capacity of different traditional medicine and ethnomedicine knowledge can be used as good sources for new drug discovery after accurate studies.
Background: Since December 2019, the outbreak of corona virus pneumonia was observed in China and quickly propagate in all of the world. Nowadays many trials are underway on this disease in which the efficacy of various therapeutic remedies including chemical or natural agents as well as different non pharmacological methods such as acupuncture are evaluated. This study aims at investigating the effect of M. communis fruit for treatment of COVID-19 disease.Methods: We are performing an open label randomized controlled trial on outpatients clinically suspected to COVID-19 disease in the age range of 18-65 years old with mild to moderate symptoms and without respiratory distress. Patients in both groups (M. communis and control) receive conventional therapy, but those in M. communis group get M. communis preparation in addition to conventional therapy. Intervention will continue for 5 days and the study outcomes including clinical statues as well as mortality rate and adverse effects will be measured up to 14 days.Discussion: The protocol describes the design of an ongoing randomized controlled trial to establish the evidence for the usage of water extract of M. communis fruit in clinically suspected COVID-19 disease and identify any safety concerns.Trial registration: The trial has been registered at the Iranian Registry of Clinical Trials website under the code IRCT20180923041093N3 on March 28th, 2020 (https://www.irct.ir/trial/46721). The results will be disseminated through manuscript publications, and presentations to scientific meetings.
Background:
Non-Alcoholic Fatty Liver Disease (NAFLD) is one of the most
prevalent liver diseases regarded as the primary cause of chronic liver disease, which may
lead to hepatic failure. Despite the recent developments in the treatment of NAFLD, the necessity
to find more efficient treatments has led to investigation on medicinal plants. Traditional
Persian Medicine (TPM) is one of the oldest medical schools in the world. For treatment
of NAFLD, different medicinal plants have been employed in TPM.
Objective:
Considering the public welcome for herbal medicines, the current evidence-based
review study is conducted to investigate herbal remedies for NAFLD in TPM.
Methods:
Medicinal plants for treating NFALD were extracted according to three famous
textbooks of Persian medicine. Then anti-obesity, hypolipidemic, hypoglycemic, antioxidative
and hepatoprotective effects of these medicinal plants were investigated according
to modern medicine. For this purpose, databases including Scopus, web of sciences, Pubmed,
Google scholar and science direct were searched.
Results:
Investigations of Persian medicine textbooks resulted in deriving 53 herbs, which
are useful for treating NAFLD. Searching through aforesaid databases showed that most of
these plants can help to treat this disease in at least 2 ways. 25 herbs are effective in all 5
mentioned effects.
Conclusion:
It should be considered that in Persian medicine, first-line treatment is correction
of life style, then if necessary, herbs are prescribed. However, this study showed that
many herbs mentioned in Persian medicine for treatment of NAFLD might have a potential
to aid patient with this disease.
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