Calcifications or hard tissue deposits in the wall of keratocystic odontogenic tumor (KCOT) are rare and uncommon. Three types of calcifications have been reported in the literature: dystrophic, cartilagenous, dentinoid. A case of maxillary KCOT with calcification is reported with a review on prevalence and pathogenesis of these calcifications. The calcifications associated with the connective tissue of keratocystic odontogenic tumor were studied using special stains. These calcifications were positive for collagen stains, Van Gieson, Masson trichrome, and negative for congo red and mallory suggesting that these irregularly shaped, diffuse calcifications which form on a collagenous matrix are dysplastic dentin.
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