Calendula suffruticosa Vahl subsp. boissieri Lanza is well-known for its medicinal properties in northeastern Algeria. As far as literature has been able to prove, no study has attempted to make a phytochemical or biological activity evaluation (antioxidants, enzyme inhibitors and antimicrobial potential). This work intends to evaluate, for the first time, the chemical constituents and study the previously mentioned biological activities of C. suffruticosa boissieri essential oil and different sections (flowers, leaves, roots) as well as the effect of changing the solvent (ethanol 70 %) and (methanol 70 %) on these activities. The essential oil of aerial parts of this plant was investigated using GC/MS, and 45 compounds were discovered, accounting for 98.01 % of the essential oil, including 23 monoterpenes, 6 sesquiterpenes, 12 diterpenes, 1 coumarin, 3 alkanes, methyl-cyclohexane (23.73 %), limonene (25.02 %), and o-cymene (13.20 %). Five methods were used to study the antioxidant activity (ABTS, DPPH, CUPRAC, reducing power, and β-carotene bleaching assay), where the results were impressive, especially for the essential oil. In addition, the hydroethanolic solvent (70 %) was found to be the most effective solvent for extraction in general compared to the hydromethanolic solvent (70 %). The extracts and essential oils of C. suffruticosa boissieri also showed a strong inhibiting ability against cholinesterase, tyrosinase, anti-αamylase, α-glucosidase, and antimicrobials, a very valuable antioxidant, which is a real discovery. Based on these results, it can be said that this plant has important biological activities, so it can be used in the phytotherapy, food, or pharmaceutical sectors.
Euphorbia species possess pharmacological properties that have been widely used for medical purposes worldwide. In this paper, three plants belonging to the Euphorbia genus growing in North-East of Algeria were studied. The phenolic contents were identified using LC-MS, while the fatty acid composition of their fixed oils was determined with GC-MS. The quantification of the total condensed tannins and the leaves' entire anthocyanin content were performed using photometric methods. The main constituents of the polyphenolic compounds identified by LC-MS were ascorbic, chlorogenic, and ellagic acids. The oil yield of the seeds of E. terracina, E. biumbellata, and E. dendroides was 17.48%, 18.5%, and 20.05%, respectively. Quantitative analyses of these oils using GC-MS showed variations in the species' fatty acid constituents' concentrations and compositions. Besides, the phytochemical screening results showed that E. terracina possessed a high amount of tannin and anthocyanin content compared with other studied plants.
Background: Calendula suffruticosa subsp. monardii (Boiss. & Reut.) Ohle, a medicinal plant from the Mediterranean region and, more precisely, from the extreme northeast of Algeria, is characterized by its wide use in the traditional medicine of the local population. This is what prompted us to investigate some pharmacological benefits such as anti-diabetes and Alzheimer's activities, in addition to anti- oxidant activity. The effects of extraction methods and solvents on the amount of phenolic profiles and the biological ac- tivity of the different parts of this plant were studied, where the aim was to obtain a high extraction yield of bioactive compounds and consequently high biological activities. Methods: In vitro standard procedures were used to assess enzyme inhibitory activity (AChE, BChE, α- Amylase and α-Glucosidase) of Calendula monadii, and the antioxidant activity was assessed using the DPPH, ABTS, CUPRAC, Reducing power and Ferrous ions assays. Results: When using ultrasound, a significant increase in the amounts of (TPC, TFC and TFlas) and an- tioxidant activity (DPPH, ABTS, CUPRAC, Reducing power and Ferrous ions cheating assay) in addi- tion to the inhibitory activity of enzymes (AChE, BChE, α-Amylase α-Glucosidase) was found, com- pared to the results of conventional extraction. Furthermore, the aqueous solvent of ethanol 70% is the very effective solvent for extraction compared to methanol 70% aqueous solvent. Conclusion: Based on these results, it can be said that this plant contains important biological activities, so it can be used in phytotherapy.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.