A 40-year-old woman had been suffering from many symptoms of Behçet's disease (BD) since her childhood without being diagnosed. She had recurrent mouth ulcers and, from the age of 21, vulva ulcers followed by loss of vision due to central retinitis and later also ankle arthritis. At the age of 31, uveitis due to BD was diagnosed. The fact that BD is often not recognized in Bangladesh explains the marked delay in her diagnosis. The initial central retinitis responded well to oral glucocorticoids, azathioprine, and cyclosporine, but in the course of time she became refractory to these agents. Considering her financial constraints, low dose Infliximab (3mg/kg) was used and resulted in a remarkable but temporal improvement. She went into remission by using a regimen of 5 mg/kg with increased interval time. In this article, the treatment options for ocular involvement in BD patients are summarized. Conclusions: In countries like Bangladesh, the diagnosis of Behçet's disease can be delayed. The early cooperation of dermatologists and eye surgeons with rheumatologists is necessary. Most cases of resistant ocular BD today can be successfully treated with anti-TNF agents. Promising results are published with other biologics for refractory and multi-resistant cases.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.