Background: Alzheimer’s disease (AD) negatively impacts patients’ ability to make advantageous decisions, i.e., a core ability contributing to the preservation of autonomy. Objective: The present study aims to analyze the changes that occur in the decision-making competence (DMC) in AD patients and to determine if these changes are related to the deterioration of executive functions and working memory. Method: To this end, 20 patients with AD and 20 elderly control adults were assessed using executive, working memory, and DMC tasks. The latter comprised the Iowa Gambling Task (IGT) and a scenarios task based on situations inspired by everyday life and performed under conditions of risk and ambiguity. Results: Results revealed lower performances in AD patients than in elderly control adults for all the tasks assessing cognitive functions. The AD patients also made more strategy changes during the IGT. In the scenarios tasks, the two groups took as many ambiguous or risky decisions, but AD patients tended to take more risks in the context of gain than elderly control adults did. Switching and updating ability, as well as working memory, appeared to be involved in decisions in tasks inspired by everyday life, while inhibition was more related to the IGT performances. Conclusion: Working memory and executive functions seem to be involved in decision-making, but in different ways in gambling and daily-life situations.
Cognitive modifications over ageing can affect decision making competence (DMC). As it is a core ability in autonomy preservation, our study aims to investigate its changes in old adults and to determine if they are linked to the deterioration of executive functions and working memory. For this purpose, 50 young adults and 50 old adults were assessed with executive, working memory and DMC tasks. The latter comprised the Iowa Gambling task (IGT) and a scenarii task based on daily life-inspired situations, under risk and under ambiguity conditions. Results revealed lower performances in old adults compared to young adults for updating, inhibition and working memory tasks. The IGT failed to distinguish the two groups of age, but the scenarii task did it, as young adults were more risk and ambiguity seekers than old adults. Moreover, updating and inhibition capacities appeared to influence DMC.
Cognitive modifications over ageing can affect decision making competence (DMC). As it is a core ability in autonomy preservation, our study aims to investigate its changes in old adults and to determine if they are linked to the deterioration of executive functions and working memory. For this purpose, 50 young adults and 50 old adults were assessed with executive, working memory and DMC tasks. The latter comprised the Iowa Gambling task (IGT) and a scenarii task based on daily life-inspired situations, under risk and under ambiguity conditions. Results revealed lower performances in old adults compared to young adults for updating, inhibition and working memory tasks. The IGT failed to distinguish the two groups of age, but the scenarii task did it, as young adults were more risk and ambiguity seekers than old adults. Moreover, updating and inhibition capacities appeared to influence DMC.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.