Resilient cities provide a new operating mechanism for sustainable urban development and can effectively reduce urban disaster losses. Urban resilience has become an important research topic, but few scholars focus on the urban resilience of urban agglomerations in western China. Therefore, this paper takes the Chengdu–Chongqing urban agglomeration of China as the study area and aims to evaluate the resilience level of cities in typical regions of western China. This study uses multiple interdisciplinary methods, such as the entropy weight method, Theil index, and geographically and temporally weighted regression, to evaluate the resilience levels of 16 cities in the region and discuss the influencing factors of regional urban resilience. The results show that the urban resilience of cities in the Chengdu–Chongqing urban agglomeration has evolved from a low to high level. Additionally, there are significant spatial differences in urban resilience in the Chengdu–Chongqing urban agglomeration, and the resilience levels of cities in the east and west of the region are relatively high, while the resilience levels of cities in the south and north are relatively low. Further research found that factors such as administrative level, marketization level, industrial structure, population density, urbanization level, and emergency facility level all have a significant positive impact on the improvement of urban resilience, but this impact has spatial and temporal heterogeneity. Based on the above research results, the strategies have been proposed from the perspective of sustainable urban development to provide a new theoretical support and decision-making reference for improving the resilience level of urban agglomerations in western China.
In order to support the green and low-carbon transformation of China’s construction industry and accomplish the dual carbon objective, it is vital to accelerate green technology innovation. Therefore, this paper takes the Chengdu–Chongqing urban agglomeration of China as the study area, using the super-efficiency slacks-based measure (SBM)model and the gravity model to assess the efficiency of green technology innovation in the construction industry, utilizing geographical detectors to investigate the drivers of green technology innovation in the construction industry further. Additionally, we consider each influencing factor’s level of impact on the efficiency of green technology innovation in the construction sector both under the single factor and double factor scenarios. The findings indicate that there is a considerable difference in the efficiency of green technology innovation in the Chengdu–Chongqing metropolitan agglomeration’s construction industry, and the trend is upward. In addition, the research area exhibited spatially heterogeneous characteristics in terms of the efficiency of green technology innovation in the construction industry, and the spatial spillover effect was significantly limited by distance. Further research revealed that environmental legislation, economic development, public environmental concern, urbanization level, and foreign direct investment were the primary driving factors of green technology innovation efficiency in the construction sector, and industrial size was the potential driving factor. The spatial and temporal differentiation of the green technology innovation efficiency in the construction industry was also more affected by the interaction between the dominating factor and the prospective factor than by either factor acting alone. The research’s findings are useful in advancing the green and low-carbon transformation of the construction sector in the Chengdu–Chongqing metropolitan agglomeration by offering theoretical support and decision-making reference.
The construction industry is the lifeblood of the national economy; thereby, to some extent, the green transformation of the construction industry is representative of the industrialization levels of modern construction, especially in China. Based on the panel data of A-share listed companies in China’s construction industry from 2014 to 2019, this work studies the influence mechanism of political connection on corporate green innovation by establishing a multiple regression model, analyzes the realization path of corporate social responsibility as an mediating variable on the impact of political connections on corporate green innovation, and reveals the role boundary of environmental public opinion as a moderating variable on the impact of political connections on corporate green innovation. The results show that political connection has a significant positive impact on corporate green innovation, and this impact exists in both state-owned and non-state-owned enterprises, as well as in the eastern region and the central and western regions of China. Moreover, corporate social responsibility plays a partial mediating role in the relationship between political connection and corporate green innovation, and serves as an effective value transfer intermediary, a benefit balance mechanism, and a risk avoidance method. Political connections urge enterprises to be more socially responsible, thus affecting green innovation. Additionally, environmental public opinion strengthens the positive impact of political connections on corporate green innovation, especially in non-state-owned enterprises and in the eastern regions with a higher degree of marketization. The research conclusions provide a new theoretical reference for promoting the transformation of green innovation and achieving high-quality development in the construction industry.
Activin A, a multifunctional cytokine, is a member of transforming growth factor-β (TGF-β) superfamily. It is associated with a variety of pathophysiological processes, including inflammation, fibrosis, and tumorigenesis. Chronic or prolonged endoplasmic reticulum (ER) stress can lead to cells apoptosis. However, whether ER stress-related proteins, such as CHOP, GADD34 are involved in activin A-induced myeloma cell apoptosis remains unknown. In the present study, it was revealed that activin A inhibited the proliferation of myeloma cell line NS-1 cells and induced NS-1 cell apoptosis. Activin A upregulated the expression of CHOP, GADD34, caspase-3, and caspase-12. Moreover, both Smad3 and p-Smad3 levels were increased with treatment of activin A. Further studies revealed that the overexpression of activin signaling protein Smad3 in NS-1 cells increased the levels of CHOP, caspase-3, and p-Smad3. These data indicated that the CHOP protein of the ER stress pathway may be involved in activin A-induced NS-1 cell apoptosis, and also indicated the potential therapy of activin A-induced apoptosis via CHOP signaling for multiple myeloma.
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