2019
DOI: 10.3892/or.2019.7382
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Abstract: Activin A, a multifunctional cytokine, is a member of transforming growth factor-β (TGF-β) superfamily. It is associated with a variety of pathophysiological processes, including inflammation, fibrosis, and tumorigenesis. Chronic or prolonged endoplasmic reticulum (ER) stress can lead to cells apoptosis. However, whether ER stress-related proteins, such as CHOP, GADD34 are involved in activin A-induced myeloma cell apoptosis remains unknown. In the present study, it was revealed that activin A inhibited the pr… Show more

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Cited by 4 publications
(1 citation statement)
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“…PCR products were separated by 2% agarose gel electrophoresis and stained with Super Gelred (US EVERBRIGHT, Suzhou, China). The specific bands were analyzed using Image J software and the expression levels of these genes were normalized against GAPDH 50 . Primers sequences were available upon Table 1 .…”
Section: Methodsmentioning
confidence: 99%
“…PCR products were separated by 2% agarose gel electrophoresis and stained with Super Gelred (US EVERBRIGHT, Suzhou, China). The specific bands were analyzed using Image J software and the expression levels of these genes were normalized against GAPDH 50 . Primers sequences were available upon Table 1 .…”
Section: Methodsmentioning
confidence: 99%