The development of nonorthogonal tandem catalysis enables the use of a combination of arbitrary catalysts to rapidly synthesize complex products in a sustainable, efficient, and timely manner.
Cross-linked micelles have emerged as promising catalyst supports over the past two decades due to their improved structural stability, chemical diversity in multiple domains, and catalyst recovery compared to their uncross-linked analogues. We highlight the different physicochemical properties that arise by cross-linking the shell or core-domain and the subsequent impact on catalysis. Both, shell cross-linked micelles (SCMs) and core cross-linked micelles (CCMs) were initially designed to include one catalytic entity. Later on, SCMs were used to compartmentalize catalysts for non-orthogonal tandem catalysis while CCMs were investigated as phase transfer agents in biphasic catalysis. Current challenges in this field and new design trends for advanced micellar nanoreactors are discussed.
We describe the substrate-selective
asymmetric transfer hydrogenation
of aromatic ketones using rhodium complexes immobilized on a photoresponsive
nanoreactor. The nanoreactor switches its morphology upon light irradiation
in a wavelength-selective manner. Kinetic studies show that the gated
behavior in the cross-linking layer is key to discriminating among
substrates and reagents during catalysis. Under ultraviolet light
irradiation, the nanoreactor displays substrate selectivity, converting
smaller ketone substrates faster to the corresponding secondary alcohols.
We report the dendron-shaped macromolecules ABn crystallize into well-ordered pyramid-like structures from mixed solvents, instead of spherical motifs with curved structures as found in bulk. The design of the asymmetric...
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.