Solid phase one-pot Multicomponent reaction was used widely to achieved a board spectrum of heterocyclic compounds due to it’s supreme properties starting from four component mixture of piperonal binzil, p-phenylene diamine and ammonium acetate which was reacted directly through grinding then microwave irradiation at (270 watt) for (8 min) in a cidic media to afford 1-N(p-aminophenyl)-2-(piperonyl-5-yl)-5-hydroxy-4, 5-diphenyl-2H-imidazole (1) which then converted to its N'-aroyl derivatives (2-4) through it’s reaction with substituted benzoyl chloride in basic media terminated by direct reaction with acetic anhydride to obtained N'-acetyl-N'-aroyl derivative (5-7) followed by inter cyclization reaction with hydrazine hydrate (99%) to achieve 1,2,4-trizole derivatives (8-10) in basic media. The assigned structure of the prepared compounds were corroborated by the available physical and spectral methods.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.