Unilateral hyperplasia of the mandibular condyle must be ascribed to a persistent or resumed activity of the precartilaginous cells of the condylar growth zone (Rushton, 1946). Normally the active formation of cartilage gradually comes to a stop at about 20 years of age. Simultaneously the replacement of cartilage by bone ceases. The bone then forms a continuous plate interposed between the cartilage and the marrow cavity. Inactive remnants of the prec.artilaginous layer persist and its cells may be aroused to new activity, as for instance in acromegaly (Rush-: $ The authors are indebted to Professor B. Engfeldt, Upsala, for valuable advice during the course of the investigation. Financial aid was received from Konung Gustaf V : s 80-drsfond and Reseruationsanslaget for friimjande av medicinsk forskning; and from the National Institutes of Health (RG-6491 Mult.), Bethesda, Md. and the John R . Hartford Foundation, Inc. ;$+Research Fellow, The Helen Hay Whitney Foundation, on leave of absence from Karolinska Institutet and the Royal School of Dentistry, Stockholm, Sweden. Acta Odontol Scand Downloaded from informahealthcare.com by Nyu Medical Center on 04/13/15 For personal use only. 35 -Acta odont. scand. Vol. 20 Acta Odontol Scand Downloaded from informahealthcare.com by Nyu Medical Center on 04/13/15 For personal use only. * The isotope was supplied as carrier-free sulfate by the Radiochemical Centre, Amersham, England. Acta Odontol Scand Downloaded from informahealthcare.com by Nyu Medical Center on 04/13/15 For personal use only. Acta Odontol Scand Downloaded from informahealthcare.com by Nyu Medical Center on 04/13/15 For personal use only. Acta Odontol Scand Downloaded from informahealthcare.com by Nyu Medical Center on 04/13/15For personal use only.-D~--1916 : V n i l a t e r d hyperplasin of t h e mandibular condyle. I'roc. roy.Soc. JIetl. 59: 431.-P--
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