Objective: COVID-19 is caused by SARS-CoV-2. Although pulmonary manifestations have been identified as the majorsymptoms, several hematological abnormalities play a vital role in disease treatment and monitoring. This study summarizesthe hematological abnormalities (platelets, white blood cells, hemoglobin, coagulation alterations) as well as changes ininflammatory markers.Study Design And Setting: A retrospective cross-sectional study was conducted among PCR positive COVID-19 patients.The study was conducted at pathology department of CMH Malir between Aug 2021 and Jan 2022.Methodology: All the individuals with positive real-time reverse transcription-polymerase chain reaction (PCR) resultswere involved in the study. One hundred and twenty six COVID-19 patients were included using convenience sampling.Six ml venous blood was collected and analyzed. The data were entered and analyzed using SPSS version 23.Results: Among 126 patients different hematological and inflammatory parameters were noted. Significantly raised CRP,ESR in 96.8% and 92.9 % were noted respectively. Other parameters like raised D-dimers was found in 60.3 %, leukocytosis65.1%, neutrophilia in 62.7 %. Significantly elevated neutrophil lymphocyte ratio was seen in 62 % of patients. Parameterslike anemia and prolonged PT / APTT were not significant.Conclusion: The study concluded that CRP, ESR, leukocytosis, neutrophilia, elevated Neutrophil to lymphocyte ratio andD-dimers are significantly raised among serious patients with COVID-19 disease and can be used as monitoring, prognosisand severity index.
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