Background: Blood groups have been the subject of research because of the importance of blood transfusion in surgery as well as treatment of anemia and other hemorrhagic conditions. Blood groups and immune hematological problems of blood transfusion constitute an extremely interesting, but complex study area and their investigations have much to offer to hematology and immunohematology fields. Aim: The aim of our study is to provide essential data about the distribution of ABO and Rhesus blood groups among Saudi populations and to determine the ABO and Rh phenotype among patients who received blood or blood products in King Abdulaziz Medical City-Riyadh. Methods: For this purpose, we retrospectively evaluated the results of ABO grouping and Rh grouping performed among some patients who received blood or blood products at King Abdulaziz Medical City Riyadh during the year 2013. Results: Participants in this study included four hundred patients (100 children; 28 youths, 88 adults and 184 olds). The gender distribution showed 232 males and 168 females. ABO phenotypes result showed that blood group A is 27%, group B 22%, group AB 3%, and group O is 48%. The percentages of positive and negative Rh grouping phenotypes were 96% and 4%, respectively. Conclusion: In conclusion, our study shows that the blood group O is highly frequent among Saudi population, while the blood group AB is the lowest. Rh-negative phenotypes were not as frequent as Rh-positive.
Background:The Rhesus (Rh) blood group system is one of the most polymorphic and immunogenic systems known in humans, because of its immunogenicity along with ABO grouping, RhD antigen testing was made mandatory before issuing a compatible blood. At present, there are five major antigens, i.e., D, C, E, c, and e in Rh blood group system.Aims:The aim of this study is to provide essential data about the distribution of the major Rh antigens and the most common phenotype among the Saudi population.Materials and Methods:This is a retrospective study to evaluate the Rh grouping and Rh sub-groups performed among some donors who donated blood or blood products at the department of donation center at King Abdulaziz Medical City Riyadh, Saudi Arabia from January 1, 2014 to December 31, 2014. Sample size included 600 donors. Donors are males and females and their ages are above 18 years.Results:The incidence of RhD was 84.8% and only 15.2% of samples were negative for D antigen. The Incidence of other Rh antigens C, E, c, and e were 62.3%, 23.5%, 74.3%, and 95.0%, respectively. The most common phenotype among RhD positive donors was DCcee (28.7%) and among RhD negative donors was dccee (13.7%). However, three donors (0.5%) were negative for antithetical antigens C and c.Conclusion:This study shows that there is a wide racial and geographical variation in the distribution of Rh antigens and phenotypes among study participants. The Rh blood group system has a vital role in population genetic study and in resolving medical legal issues and more importantly in transfusion medicine practice.
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