The P atom in the title compound, C19H29N4O4P, exhibits a tetrahedral coordination and the phosphoryl and carbonyl groups are anti to each other. Adjacent molecules are linked by N—H⋯O hydrogen bonds to form a layer motif.
The crystal structures of two single-enantiomer amidophosphoesters with an (O) 2 P(O)(N) skeleton, i.e. diphenyl [(R)-(+)--methylbenzylamido]phosphate, (I), and diphenyl [(S)-(À)--methylbenzylamido]phosphate, (II), both C 20 H 20 -NO 3 P, are reported. In both structures, chiral one-dimensional hydrogenbonded architectures, along [010], are mediated by N-HÁ Á ÁOP interactions. The statistically identical assemblies include the noncentrosymmetric graph-set motif C(4) and the compounds crystallize in the chiral space group P2 1 . As a result of synergistic co-operation from C-HÁ Á ÁO interactions, a two-dimensional superstructure is built including a noncentrosymmetric R 4 4 (22) hydrogenbonded motif. A Cambridge Structural Database survey was performed on (O) 2 P(O)(N)-based structures in order to review the frequency of space groups observed in this family of compounds; the hydrogen-bond motifs in structures with chiral space groups and the types of groups inducing chirality are discussed. The 2,3 J X-P (X = H or C) coupling constants from the NMR spectra of (I) and (II) have been studied. In each compound, the two diastereotopic C 6 H 5 O groups are different, which is reflected in the different chemical shifts and some coupling constants.
In the title compound, C14H30N3OP, both cyclohexyl groups adopt chair conformations with the NH unit in an equatorial position. The P atom adopts a slightly distorted tetrahedral environment. In the (CH3)2NP(O) unit, the O—P—N—C torsion angles, showing the orientations of the methyl groups with respect to the phosphoryl group, are −166.6 (3) and 34.6 (4)°. The O atom of the P=O group acts as a double hydrogen-bond acceptor and is involved in two different intermolecular N—H⋯OP hydrogen bonds, building R
2
2(8) rings that are further linked into chains running parallel to the b axis.
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