Background: Herpes simplex virus type-2 could hardly lead to encephalitis in human-being. Some DNA viruses could be reactivated by COVID-19 infection such as HSV-1 and HSV-2 viruses. An uncommon presentation of HSV-2 was detected as cerebellitis in this patient. It could be concluded that SARS COVID-2 can reactivate DNA viruses such as HSV-2.
Case Presentation: Here we report a one-year-old girl infant with cerebellum involvement secondary to herpes simplex virus type 2 infection.
Conclusion: The patient was treated for three weeks with intravenous acyclovir and oral prednisolone. Finally, during her neurological follow-ups in a 9 months period of time, she was able to walk with minimal ataxia.
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