Background: Trophoblastic diseases are in general exclusive to women in their reproductive years. Gestational choriocarcinoma (GC) is a rare malignant tumor derived from the trophoblast of women in childbearing age. Our objective was to study the epidemiological and clinicopathologic aspects at the laboratories of pathological anatomy and cytology (ACP) of Aristide Le Dantec Hospital and General Idrissa Pouye Hospital.Methods: Our study was conducted in the anatomy and pathology laboratories of the Hôpital Général Idrissa Pouye and the Hôpital Aristide Le Dantec in Dakar. This study was based on records of pathological reports of gestational choriocarcinomas from these different laboratories. This was a retrospective and descriptive bi-centric study, spread over eight (8) years from January 1, 2013, to December 31, 2020. All cases diagnosed on hysterectomy specimens and with a formal conclusion of choriocarcinoma have been included. We recorded the data collected in Excel 2007 software and the analysis was made using Epi Info.Results: We collected 25 cases of choriocarcinomas. The mean age of the patients was 38.1±9.7. Mixed seat tumors (intra-cavitary and intra-mural) were the most frequent with 48% of cases. Patients who were at FIGO stage 1 represented for 88% of cases.Conclusions: Gestational choriocarcinoma (GC) is a proliferation of the trophoblast (cytotrophoblast and syncitiotrophoblast). This study has helped establish histopathological data of choriocarcinoma on hysterectomy specimen in Dakar.
Intestinal metaplasia of the bladder is a rare pathology, estimated at less than 1% of bladder pathologies. Some forms, including pseudo tumor glandular cystitis, can mimic cancer. We report a rare case of this pathology, little studied in our context, treated in Senegal and we underline the epidemiologicalclinical and anatomopathological particularities. Observation: Mr. MN, 26 years old, non-smoking, known epileptic, with psychomotor delay since birth (under Tegretil and Gardenal), presented with a hip’s trauma, not operated on in 2012, then a left leg fracture following a traffic accident in August 2019. He consulted for recurrent terminal hematuria without urination burn, dysuria and pelvic pain. The clinical examination revealed a motor deficit, a normal prostate on rectal examination. Cystoscopy showed a solid, vegetative, ulcerated tumor lesion of the bladder, of trigonal location and of the right lateral wall without invasion sign, with ureteral meatus and permeable ureters. The rest of the devices and biological assessments examination are unremarkable. Abdomino-pelvic ultrasound revealed a semi-replete bladder with a non-significant post-void residue and 39.78 cc prostatic hypertrophy without repercussions on the upper urinary system. The patient underwent a complete and deep bladder’s transurethral resection which, after histological examination, showed a pseudotumoral glandular cystitis of the bladder. Conclusion: The bladder should be taken into account in adult patients, often males, with irritative and obstructive urinary signs. It can occur without previous bladder infection. This pathology can simulate bladder cancer from which the interest of the pathological examination which makes it possible to make the formal diagnosis.
Background: Objectives of the study were to record the results of uterine cervical smear tests of women in the Diourbel region to compare epidemiological data with the results of uterine cervical smear tests.Methods: This was a retrospective study of 201 satisfactory cervical smears performed in the period from 01 December 2018 to 01 December 2019 at the laboratory of the regional hospital Henrich Lubcke of Diourbel. All women with a satisfactory smear were included in our study, so we classified patients according to age and parity.Results: The mean age of the patients was 38.41 years with a standard deviation of 11.51 years. The extremes were 15 and 64 years. The age group (30-40 years) was in the majority at 32.34%. Multiparous patients were in the majority, accounting for 43.28%. The cervix was macroscopically healthy in 61.19% of patients and inflammatory in 12.94%. There was 18.41% low-grade squamous intraepithelial lesion (LSIL), high-grade squamous intraepithelial lesion (HSIL) accounted for 1% of smears. A statistically significant relationship existed between parity and smear result with p˂0.01.Conclusions: Cervical cancer is one of the most fatal cancers in women and the smear remains the safest and most effective means of prevention.
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